Staff
Dr. Bertzbach, Luca
Postdoctoral Fellow Viral TransformationPublications
Bertzbach LD, Ip WH, von Stromberg K, Dobner T, Grand RJ (2024). A comparative review of adenovirus A12 and C5 oncogenes. Curr Opin Virol. 67/2024; PubMed
Denesvre C, You Y, Rémy S, Vychodil T, Courvoisier K, Penzes Z, Bertzbach LD, Kheimar A, Kaufer BB (2024). Impact of viral telomeric repeat sequences on herpesvirus vector vaccine integration and persistence. PLoS Pathog. 20/2024; PubMed
Bertzbach LD, Seddar L, von Stromberg K, Ip W-H, Dobner T, Hidalgo P (2024). The adenovirus DNA-binding protein DBP. J Virol. 98/2024; PubMed
You Y, Kheimar AM, Vychodil T, Kossak L, Sabsabi MA, Conradie AM, Reddy SM, Bertzbach LD, Kaufer BB (2024). Telomeric repeats in the commercial SB-1 vaccine facilitate viral integration and contribute to vaccine efficacy. NPJ Vaccines. 9/2024; PubMed
Ip WH, Fiedler M, Gornott B, Morische M, Bertzbach LD, Dobner T (2024). Cellular SUMO-specific proteases regulate HAdV-C5 E1B-55K SUMOylation and virus-induced cell transformation. Front Cell Infect Microbiol. 14/2024; PubMed
Hidalgo P, Torres A, Jean Beltran PM, López-Leal G, Bertzbach LD, Dobner T, Flint SJ, Cristea IM, González RA (2024). The protein composition of human adenovirus replication compartments. mBio. 2024 Nov 29; PubMed
Kheimar A, Trapp-Fragnet L, Conradie AM, Bertzbach LD, You Y, Sabsabi MA, Kaufer BB (2023). Viral and cellular telomerase RNAs possess host-specific anti-apoptotic functions. Microbiol Spectr. 11/2023; PubMed
Bertzbach LD, Kohn M, You Y, Kossak L, Sabsabi MA, Kheimar A, Härtle S, Kaufer BB (2023). In vitro infection of primary chicken lymphocytes with Marek's disease virus. STAR Protoc. 4/2023; PubMed
Kaufer BB, Parcells MS, Bertzbach LD (2023). A Special Issue on Marek's Disease Virus-The Editors' View. Microorganisms. 11/2023; PubMed
Dobner T, Bertzbach LD (2023). Updates and New Perspectives on Adenoviral Gene Therapy and Vaccine Vectors. Viruses. 15/2023; PubMed
Ip WH, Bertzbach LD, Speiseder T, Dobner T (2023). The adenoviral E4orf3/4 is a regulatory polypeptide with cell transforming properties in vitro. Tumour Virus Res. 15/2023; PubMed
Chalabi Hagkarim N, Ip WH, Bertzbach LD, Abualfaraj T, Dobner T, Molloy DP, Stewart GS, Grand RJ (2023). Identification of Adenovirus E1B-55K Interaction Partners through a Common Binding Motif. Viruses. 15/2023; PubMed
Ip W-H, Tatham MH, Krohne S, Gruhne J, Melling M, Meyer T, Gornott B, Bertzbach LD, Hay RT, Rodriguez E, Dobner T (2023). Adenovirus E1B-55K controls SUMO-dependent degradation of antiviral cellular restriction factors. J Virol. 97/2023; PubMed
von Stromberg K, Seddar L, Ip WH, Günther T, Gornott B, Weinert SC, Hüppner M, Bertzbach LD, Dobner T (2023). The human adenovirus E1B-55K oncoprotein coordinates cell transformation through regulation of DNA-bound host transcription factors. Proc Natl Acad Sci U S A. 120/2023; PubMed
Alemán MV, Bertzbach LD, Speiseder T, Ip WH, González RA, Dobner T (2022). Global Transcriptome Analyses of Cellular and Viral mRNAs during HAdV-C5 Infection Highlight New Aspects of Viral mRNA Biogenesis and Cytoplasmic Viral mRNA Accumulations. Viruses. 14/2022; PubMed
You Y, Conradie AM, Kheimar A, Bertzbach LD, Kaufer BB (2022). Correction for You et al., "The Marek's Disease Virus Unique Gene MDV082 Is Dispensable for Virus Replication but Contributes to a Rapid Disease Onset". J Virol. 96/2022; PubMed
Fiedler M, Ip WH, Hofmann-Sieber H, Wilkens B, Nkrumah FK, Zhang W, Ehrhardt A, Bertzbach LD, Dobner T (2022). Protein-Protein Interactions Facilitate E4orf6-Dependent Regulation of E1B-55K SUMOylation in HAdV-C5 Infection. Viruses. 14/2022; PubMed
Boddin J, Ip WH, Wilkens B, von Stromberg K, Ching W, Koyuncu E, Bertzbach LD, Dobner T (2022). A Single Amino Acid Switch in the Adenoviral DNA Binding Protein Abrogates Replication Center Formation and Productive Viral Infection. mBio. 13/2022; PubMed
Hidalgo P, Garcés Y, Mundo E, López RE, Bertzbach LD, Dobner T, González RA (2022). E1B-55K Is a Phosphorylation-Dependent Transcriptional and Posttranscriptional Regulator of Viral Gene Expression in Human Adenovirus C5 Infection. J Virol. 96/2022; PubMed
You Y, Vychodil T, Aimola G, Previdelli RL, Göbel TW, Bertzbach LD, Kaufer BB (2021). A Cell Culture System to Investigate Marek's Disease Virus Integration into Host Chromosomes. Microorganisms. 9/2021; PubMed
Bertzbach LD, Ip WH, Dobner T (2021). Animal Models in Human Adenovirus Research. Biology (Basel). 10/2021; PubMed
Kolbe V, Ip WH, Kieweg-Thompson L, Lang J, Gruhne J, Meyer T, Wilkens B, Schie M, Thünauer R, Schreiner S, Bertzbach LD, Rodríguez E, Dobner T (2021). Conserved E1B-55K SUMOylation in Different Human Adenovirus Species Is a Potent Regulator of Intracellular Localization. J Virol. 96/2022; PubMed
Trapp-Fragnet L, Schermuly J, Kohn M, Bertzbach LD, Pfaff F, Denesvre C, Kaufer BB, Härtle S (2021). Marek's disease virus prolongs survival of primary chicken B-cells by inducing a senescence-like phenotype. PLoS Pathog. 17/2021; PubMed
Midha A, Goyette-Desjardins G, Goerdeler F, Moscovitz O, Seeberger PH, Tedin K, Bertzbach LD, Lepenies B, Hartmann S (2021). Lectin-Mediated Bacterial Modulation by the Intestinal Nematode Ascaris suum. Int J Mol Sci. 22/2021; PubMed
You Y, Hagag IT, Kheimar A, Bertzbach LD, Kaufer BB (2021). Characterization of a Novel Viral Interleukin 8 (vIL-8) Splice Variant Encoded by Marek's Disease Virus. Microorganisms. 9/2021; PubMed
Ip WH, Wilkens B, Solomatina A, Martin J, Melling M, Hidalgo P, Bertzbach LD, Speiseder T, Dobner T (2021). Differential Regulation of Cellular FAM111B by Human Adenovirus C Type 5 E1 Oncogenes. Viruses. 13/2021; PubMed
You Y, Conradie AM, Kheimar A, Bertzbach LD, Kaufer BB (2021). The Marek's Disease Virus Unique Gene MDV082 Is Dispensable for Virus Replication but Contributes to a Rapid Disease Onset. J Virol. 95/2021; PubMed