Ongoing Projects
Here you will find an overview of current SARS-CoV-2 research projects at LIV:
Emergence and Origin of SARS-CoV-2 Mutations - Intrahost SARS-CoV-2 Genetic Diversity in Immunocompetent and Immunosuppressed Patients
Prof. Dr. Adam Grundhoff (Research Unit Virus Genomics)
Corona Consortium: Plasma-based disinfection of the respiratory tract to reduce SARS-CoV-2 viral load in vitro and in vivo (PlasmaplusCorona, PPC)
Prof. Dr. Gülsah Gabriel (Research Department Viral Zoonosis - One Health)
Corona Consortium: Development of a new therapeutic approach against COVID-19 (Targeted elimination of SARS-CoV-2 by microparticle-based high-affinity virus-binding conjugates, ViKon)
Prof. Dr. Gülsah Gabriel (Research Department Viral Zoonosis - One Health)
Studies on the pathogenicity and transmissibility of SARS-CoV-2 compared to SARS-CoV, MERS-CoV and influenza in different animal models
Prof. Dr. Gülsah Gabriel (Research Department Viral Zoonosis - One Health)
Molecular epidemiology of the SARS-CoV-2 pandemic in the Hamburg metropolitan region | Genetic variability and tissue /cell tropism of SARS-CoV-2
Prof. Dr. Adam Grundhoff (Research Unit Virus Genomics)
Structure and function of coronaviral replication and transcription complexes by mass spectrometry
Dr. Charlotte Uetrecht (Junior Research Group Dynamics of viral Structures)
Light microscopic and electron microscopic examination of SARS-CoV-2 infected samples | Cryo-electron microscopic structural investigations
Prof. Dr. Jens B. Bosse (Associated Group Quantitative Virology)
Prof. Dr. Kay Grünewald (Research Department Structural Cell Biology of Viruses)
Research on the immune system to answer the question why the immune system of older people and men copes less well with the disease
Prof. Dr. Marcus Altfeld (Research Department Virus Immunology)
Dr. Dr. Madeleine Altfeld-Bunders (Subunit Immune Ontogeny)
Evaluation of antivirals and vaccines against SARS-CoV-2 in animal models
Prof. Dr. Gülsah Gabriel (Research Department Viral Zoonosis - One Health)
Rapid Response / Predictive pathogen detection method by mass spectrometry
Dr. Charlotte Uetrecht (Junior Research Group Dynamics of viral Structures)
Dr. Pietro Scaturro (Junior Research Group Systems Arbovirology)
Establishment of human organoids from tissue samples of SARS-CoV-2 positive and negative patients | Recognition of the infected organoids by immune cells | Investigation of the immune cell activity
Prof. Dr. Marcus Altfeld (Research Department Virus Immunology)
Dr. Dr. Madeleine Altfeld-Bunders (Subunit Immune Ontogeny)
Establishment of a reverse genetics system for cloning and targeted modification of the SARS-CoV-2 genome | Characterization of genetic variants and pathogenicity factors
Prof. Dr. Wolfram Brune (Research Department Virus-Host-Interaction)