• Electron Cryo Microscopy/Tomography (cryoEM/cryoET)
  • Integrative Structural Biology
  • Fluorescence and Light Microscopy (multiple modalities including TIRF, confocal etc.)
  • Super-resolution Fluorescence Microscopy (various localization microscopies, SIM etc.)
  • Correlation Cryo Microscopy (combination of Fluorescence Cryo Microscopy with Electron Cryo Microscopy or Soft X-ray Cryo Microscopy)
  • Image Processing
  • Computational Biology
  • X-ray Crystallography
  • Mass Spectrometry
  • Cell Biology
  • Dedicated in vitro subcellular experimental systems of various levels of complexity
  • Molecular Biology
  • Protein Biochemistry
  • Protein-Protein-Interactions
  • Protein-Lipid Interactions (membrane proteins, fusion proteins, Membrane modulation by proteins)

Recent Publications

Ferreira JL, Pražák V, Vasishtan D, Siggel M, Hentzschel F, Binder AM, Pietsch E, Kosinski J, Frischknecht F, Gilberger TW, Grünewald K (2023). Variable microtubule architecture in the malaria parasite Nat Commun 14, 1216 (2023).

Williams HM, Thorkelsson SR, Vogel D, Milewski M, Busch C, Cusack S, Grünewald K, Quemin ERJ, Rosenthal M (2023). Structural insights into viral genome replication by the severe fever with thrombocytopenia syndrome virus L protein. Nucleic Acids Res. 2023 Jan

Bücker R, Seuring C, Cazey C, Veith K, García-Alai M, Grünewald K, Landau M (2022). The Cryo-EM structures of two amphibian antimicrobial cross-β amyloid fibrils. Nat Commun. 2022 Jul 27;13(1):4356.