Genomics of Retroviral Infections

The BMBF junior research group Genomics of Retroviral Infections, headed by Dr. Dr. Ulrike Lange, is investigating the extent to which retroviruses such as HIV influence the function of the target genome and vice versa. They are investigating the molecular mechanisms that determine the selection of genomic HIV integration sites and the establishment and maintenance of HIV latency during chronic infection.

Group picture of the Junior Research Group Genomics of Retroviral InfectionsLange group 2023 © Gisela Köhler
HIV integrates into DNAHIV integrates in DNA © AdobeStock / Giovanni Cancemi

The aim is to identify new strategies for controlling retroviral infections. Among other things, they use experimental methods based on high-throughput sequencing that allow genome-wide analysis of epigenetic and transcriptional states. Current focal points are the investigation of aberrant gene transcripts in chronic HIV infection using various cell models and the establishment of bioinformatic methods to analyze the regulation of endogenous retroviruses in HIV target cells of the immune system.

Contact

Dr. Dr. Ulrike Lange

Head of Junior Research Group

Phone: +49 (0)40 48051-261

Email: Please enable JavaScript to render this link!

Team members

Graduate Student
Graduate Student
Postdoctoral Fellow
Technician
Technician
Student
Portrait von Ulrike Lange
Head of Junior Research Group
Ramon Stoeck
Student

Contact

Dr. Dr. Ulrike Lange

Head of Junior Research Group

Phone: +49 (0)40 48051-261

Email: Please enable JavaScript to render this link!