Mitarbeiterinnen und Mitarbeiter

Brito LF, Ostermann E, Tödter S, Virdi S, Indenbirken D, Brixel R, Arens R, Grundhoff A, Brune W, Stahl FR (2026). Limited protection against early-life lung murine cytomegalovirus infection results from deficiency of cytotoxic CD8 T cells. PLoS Pathog. 22/2026; PubMed

Rehm TM, Straub E, Doorbar J, Grundhoff A, Günther T, Blümke P, Iftner T, Stubenrauch F (2026). Inhibition of high risk HPV31 E8^E2 repressor activity enables differentiation-independent genome amplification and E4 expression. PLoS Pathog. 22/2026; PubMed

Hamann, M. V., Brauckmann, L., Schwarz, C., Spohn, M., Stoeck, R., Leddy, S. M., Frouard, J., Adiba, M., Winzer, R., Virdi, S., Grundhoff, A., Feschotte, C., Muecksch, F., Roan, N. R., Tolosa, E. & Lange, U. C. (2026). Selective persistence of HIV-1-infected T cell clones can occur through immune reprogramming driven by defective, transcriptionally active proviruses bioRxiv. URI

Campos-León K, Ferguson J, Günther T, Wood CD, Wingett SW, Pekel S, Varghese CS, Jones LS, Stockton JD, Várnai C, West MJ, Beggs A, Grundhoff A, Noyvert B, Roberts S, Parish JL (2025). Repression of CADM1 transcription by HPV type 18 is mediated by three-dimensional rearrangement of promoter-enhancer interactions. PLoS Pathog. 21/2025; PubMed

Wang J, Brückner N, Weissmann S, Günther T, Zhu S, Vogt C, Sun G, Guo R, Bruno R, Ritter B, Steinbrück L, Kaufer BB, Depledge DP, Grundhoff A, Viejo-Borbolla A (2025). Repression of varicella zoster virus gene expression during quiescent infection in the absence of detectable histone deposition. PLoS Pathog. 21/2025; PubMed

Bludau A, Jack A, Fischer N, Dreesman J, Drosten C, Egelkamp R, Ehlkes L, Feil F, Grundhoff A, Grundmann H, Kreuzer P, Monazahian M, Overesch I, Schmitt D, Tröger M, von Reiswitz A, Weber J, Dilthey A, Hornberg C, Reuter S, Scheithauer S (2025). Use of integrated genomic surveillance by local public health authorities: Recommendations based on a mixed-methods study of current adoption, applications and success factors, Germany, 2023. Euro Surveill. 30/2025; PubMed

Tuohinto K, Graus MS, Staab P, Tiusanen V, Liangru F, Pradhan S, Wong YY, Weissmann S, Lou J, Hinde E, Wong J, Lee Q, Terskikh A, Alvarez-Kuglen M, Karnezis T, Günther T, Grundhoff A, Sahu B, Francoís M, Ojala PM (2025). Oncogenic virus hijacks SOX18 pioneer function to enhance viral persistence. Res Sq. 2025 Aug 18; PubMed

Seddar L, von Stromberg K, Bertzbach LD, Grundhoff A, Dobner T, Ip WH (2025). Adenovirus E1B-55K regulates p53-dependent and -independent gene expression during infection. PLoS Pathog. 21/2025; PubMed

Renner, J ,Boldt, K ,Wieland, A ,Grundhoff, A ,Guenther, T, Bluemke, P ,Stubenrauch, F, Iftner, T (2025). Activation of the HPV16 late promoter by viral E2 and cellular BRD4 and ZC3H4 proteins J Virol. 99 URI

Renner J, Boldt K, Wieland A, Grundhoff A, Guenther T, Bluemke P, Stubenrauch F, Iftner T (2025). Activation of the HPV16 late promoter by viral E2 and cellular BRD4 and ZC3H4 proteins. J Virol. 99/2025; PubMed

Beschorner N, Künzle P, Voges M, Hauber I, Indenbirken D, Nakel J, Virdi S, Bradtke P, Lory NC, Rothe M, Paszkowski-Rogacz M, Buchholz F, Grundhoff A, Schambach A, Thirion C, Mittrücker HW, Schulze Zur Wiesch J, Hauber J, Chemnitz J (2024). Preclinical toxicity analyses of lentiviral vectors expressing the HIV-1 LTR-specific designer-recombinase Brec1. PLoS One. 19/2024; PubMed

Knickmann J, Staliunaite L, Puhach O, Ostermann E, Günther T, Nichols J, Jarvis MA, Voigt S, Grundhoff A, Davison AJ, Brune W (2024). A simple method for rapid cloning of complete herpesvirus genomes. Cell Rep Methods. 4/2024; PubMed

Lopez-Labrador FX, Huber M, Sidorov IA, Brown JR, Cuypers L, Laenen L, Vanmechelen B, Maes P, Fischer N, Pichler I, Storey N, Atkinson L, Schmutz S, Kufner V, van Boheemen S, Mulders CE, Grundhoff A, Blümke P, Robitaille A, Cinek O, Hubáčková K, Mourik K, Boers SA, Stauber L, Salmona M, Cappy P, Ramette A, Franze' A, LeGoff J, Claas ECJ, Rodriguez C, de Vries JJC, (2024). Multicenter benchmarking of short and long read wet lab protocols for clinical viral metagenomics. J Clin Virol. 173/2024; PubMed

Ohnezeit D, Huang J, Westerkamp U, Brinschwitz V, Schmidt C, Günther T, Czech-Sioli M, Weißelberg S, Schlemeyer T, Nakel J, Mai J, Schreiner S, Schneider C, Friedel CC, Schwanke H, Brinkmann MM, Grundhoff A, Fischer N (2024). Merkel cell polyomavirus small tumor antigen contributes to immune evasion by interfering with type I interferon signaling. PLoS Pathog. 20/2024; PubMed

Schwanke H, Gonçalves Magalhães V, Schmelz S, Wyler E, Hennig T, Günther T, Grundhoff A, Dölken L, Landthaler M, van Ham M, Jänsch L, Büssow K, van den Heuvel J, Blankenfeldt W, Friedel CC, Erhard F, Brinkmann MM (2023). The Cytomegalovirus M35 Protein Directly Binds to the Interferon-β Enhancer and Modulates Transcription of Ifnb1 and Other IRF3-Driven Genes. J Virol. 97/2023; PubMed

Zapatka M, Borozan I, Brewer DS, Iskar M, Grundhoff A, Alawi M, Desai N, Sültmann H, Moch H, , Cooper CS, Eils R, Ferretti V, Lichter P, (2023). Author Correction: The landscape of viral associations in human cancers. Nat Genet. 55/2023; PubMed

Czech-Sioli M, Günther T, Robitaille A, Roggenkamp H, Büttner H, Indenbirken D, Christner M, Lütgehetmann M, Knobloch J, Aepfelbacher M, Grundhoff A, Fischer N (2023). Integration of Sequencing and Epidemiologic Data for Surveillance of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infections in a Tertiary-Care Hospital. Clin Infect Dis. 76/2023; PubMed

Engelmann C, Schuhmachers P, Zdimerova H, Virdi S, Hauri-Hohl M, Pachlopnik Schmid J, Grundhoff A, Marsh RA, Wong WW, Münz C (2022). Epstein Barr virus-mediated transformation of B cells from XIAP-deficient patients leads to increased expression of the tumor suppressor CADM1. Cell Death Dis. 13/2022; PubMed

Heyer A, Günther T, Robitaille A, Lütgehetmann M, Addo MM, Jarczak D, Kluge S, Aepfelbacher M, Schulze Zur Wiesch J, Fischer N, Grundhoff A (2022). Remdesivir-induced emergence of SARS-CoV2 variants in patients with prolonged infection. Cell Rep Med. 3/2022; PubMed

Nörz D, Brehm TT, Tang HT, Grewe I, Hermanussen L, Matthews H, Pestel J, Degen O, Günther T, Grundhoff A, Fischer N, Addo MM, Jordan S, Hertling S, Unger S, Schäfer G, Schewe K, Hoffmann C, Aepfelbacher M, Pfefferle S, Schulze Zur Wiesch J, Schmiedel S, Lütgehetmann M (2022). Clinical characteristics and comparison of longitudinal qPCR results from different specimen types in a cohort of ambulatory and hospitalized patients infected with monkeypox virus. J Clin Virol. 155/2022; PubMed

Schlemeyer T, Ohnezeit D, Virdi S, Körner C, Weißelberg S, Starzonek S, Schumacher U, Grundhoff A, Indenbirken D, Albertini S, Fischer N (2022). Merkel Cell Carcinoma and Immune Evasion: Merkel Cell Polyomavirus Small T-Antigen‒Induced Surface Changes Can Be Reverted by Therapeutic Intervention. J Invest Dermatol. 142/2022; PubMed

Wanner N, Andrieux G, Badia-I-Mompel P, Edler C, Pfefferle S, Lindenmeyer MT, Schmidt-Lauber C, Czogalla J, Wong MN, Okabayashi Y, Braun F, Lütgehetmann M, Meister E, Lu S, Noriega MLM, Günther T, Grundhoff A, Fischer N, Bräuninger H, Lindner D, Westermann D, Haas F, Roedl K, Kluge S, Addo MM, Huber S, Lohse AW, Reiser J, Ondruschka B, Sperhake JP, Saez-Rodriguez J, Boerries M, Hayek SS, Aepfelbacher M, Scaturro P, Puelles VG, Huber TB (2022). Molecular consequences of SARS-CoV-2 liver tropism. Nat Metab. 4/2022; PubMed

Nörz D, Grunwald M, Tang HT, Weinschenk C, Günther T, Robitaille A, Giersch K, Fischer N, Grundhoff A, Aepfelbacher M, Pfefferle S, Lütgehetmann M (2022). Clinical Evaluation of a Fully-Automated High-Throughput Multiplex Screening-Assay to Detect and Differentiate the SARS-CoV-2 B.1.1.529 (Omicron) and B.1.617.2 (Delta) Lineage Variants. Viruses. 14/2022; PubMed

Hoen L, Rudisch C, Wick M, Indenbirken D, Grundhoff A, Wegwitz F, Kalkhof S, Hildebrand J (2022). Osmotic Stress Interferes with DNA Damage Response and H2AX Phosphorylation in Human Keratinocytes. Cells. 11/2022; PubMed

Nakel J, Robitaille A, Günther T, Rosenau L, Czech-Sioli M, Plenge-Bönig A, Bühler S, Wille A, Jakubowski E, Pruskil S, Wahlen M, Indenbirken D, Nörz D, Lütgehetmann M, Aepfelbacher M, Grundhoff A, Grolle B, Fischer N (2022). Comparing susceptibility and contagiousness in concurrent outbreaks with a non-VOC and the VOC SARS-CoV-2 variant B.1.1.7 in daycare centers in Hamburg, Germany. Int J Hyg Environ Health. 240/2022; PubMed

Bekere I, Huang J, Schnapp M, Rudolph M, Berneking L, Ruckdeschel K, Grundhoff A, Günther T, Fischer N, Aepfelbacher M (2021). Yersinia remodels epigenetic histone modifications in human macrophages. PLoS Pathog. 17/2021; PubMed

Ferguson J, Campos-León K, Pentland I, Stockton JD, Günther T, Beggs AD, Grundhoff A, Roberts S, Noyvert B, Parish JL (2021). The chromatin insulator CTCF regulates HPV18 transcript splicing and differentiation-dependent late gene expression. PLoS Pathog. 17/2021; PubMed

Nörz D, Grunwald M, Tang HT, Olearo F, Günther T, Robitaille A, Fischer N, Grundhoff A, Aepfelbacher M, Pfefferle S, Lütgehetmann M (2021). Rapid Automated Screening for SARS-CoV-2 B.1.617 Lineage Variants (Delta/Kappa) through a Versatile Toolset of qPCR-Based SNP Detection. Diagnostics (Basel). 11/2021; PubMed

Zhu S, Stanslowsky N, Fernández-Trillo J, Mamo TM, Yu P, Kalmbach N, Ritter B, Eggenschwiler R, Ouwendijk WJD, Mzinza D, Tan L, Leffler A, Spohn M, Brown RJP, Kropp KA, Kaever V, Ha TC, Narayanan P, Grundhoff A, Förster R, Schambach A, Verjans GMGM, Schmidt M, Kispert A, Cantz T, Gomis A, Wegner F, Viejo-Borbolla A (2021). Generation of hiPSC-derived low threshold mechanoreceptors containing axonal termini resembling bulbous sensory nerve endings and expressing Piezo1 and Piezo2. Stem Cell Res. 56/2021; PubMed

Heinrich F, Romich C, Zimmermann T, Kniep I, Fitzek A, Steurer S, Glatzel M, Nörz D, Günther T, Czech-Sioli M, Fischer N, Grundhoff A, Lütgehetmann M, Ondruschka B (2021). Dying of VOC-202012/01 - multimodal investigations in a death case of the SARS-CoV-2 variant. Int J Legal Med. 136/2022; PubMed

Brehm TT, Pfefferle S, von Possel R, Kobbe R, Nörz D, Schmiedel S, Grundhoff A, Olearo F, Emmerich P, Robitaille A, Günther T, Braun P, Andersen G, Knobloch JK, Addo MM, Lohse AW, Aepfelbacher M, Fischer N, Schulze Zur Wiesch J, Lütgehetmann M (2021). SARS-CoV-2 Reinfection in a Healthcare Worker Despite the Presence of Detectable Neutralizing Antibodies. Viruses. 13/2021; PubMed

Kveštak D, Juranić Lisnić V, Lisnić B, Tomac J, Golemac M, Brizić I, Indenbirken D, Cokarić Brdovčak M, Bernardini G, Krstanović F, Rožmanić C, Grundhoff A, Krmpotić A, Britt WJ, Jonjić S (2021). NK/ILC1 cells mediate neuroinflammation and brain pathology following congenital CMV infection. J Exp Med. 218/2021; PubMed

Koyro TF, Kraus E, Lunemann S, Hölzemer A, Wulf S, Jung J, Fittje P, Henseling F, Körner C, Huber TB, Grundhoff A, Wiech T, Panzer U, Fischer N, Altfeld M (2020). Upregulation of HLA-F expression by BK polyomavirus infection induces immune recognition by KIR3DS1-positive natural killer cells. Kidney Int. 99/2021; PubMed

Abere B, Zhou H, Li J, Cao S, Toptan T, Grundhoff A, Fischer N, Moore PS, Chang Y (2020). Merkel Cell Polyomavirus Encodes Circular RNAs (circRNAs) Enabling a Dynamic circRNA/microRNA/mRNA Regulatory Network. mBio. 11/2020; PubMed

Hamann MV, Ehmele P, Verdikt R, Bialek-Waldmann JK, Virdi S, Günther T, Van Lint C, Grundhoff A, Hauber J, Lange UC (2020). Transcriptional behavior of the HIV-1 promoter in context of the BACH2 prominent proviral integration gene. Virus Res. 293/2021; PubMed

Lotke R, Schneeweiß U, Pietrek M, Günther T, Grundhoff A, Weidner-Glunde M, Schulz TF (2020). Brd/BET Proteins Influence the Genome-Wide Localization of the Kaposi's Sarcoma-Associated Herpesvirus and Murine Gammaherpesvirus Major Latency Proteins. Front Microbiol. 11/2020; PubMed

Günther T, Czech-Sioli M, Indenbirken D, Robitaille A, Tenhaken P, Exner M, Ottinger M, Fischer N, Grundhoff A, Brinkmann MM (2020). SARS-CoV-2 outbreak investigation in a German meat processing plant. EMBO Mol Med. 12/2020; PubMed

Pfefferle S, Günther T, Kobbe R, Czech-Sioli M, Nörz D, Santer R, Oh J, Kluge S, Oestereich L, Peldschus K, Indenbirken D, Huang J, Grundhoff A, Aepfelbacher M, Knobloch JK, Lütgehetmann M, Fischer N (2020). SARS Coronavirus-2 variant tracing within the first Coronavirus Disease 19 clusters in northern Germany. Clin Microbiol Infect. 27/2021; PubMed

Elbasani E, Falasco F, Gramolelli S, Nurminen V, Günther T, Weltner J, Balboa D, Grundhoff A, Otonkoski T, Ojala PM (2020). Kaposi's Sarcoma-Associated Herpesvirus Reactivation by Targeting of a dCas9-Based Transcription Activator to the ORF50 Promoter. Viruses. 12/2020; PubMed

Manzano M, Günther T, Ju H, Nicholas J, Bartom ET, Grundhoff A, Gottwein E (2020). Kaposi's Sarcoma-Associated Herpesvirus Drives a Super-Enhancer-Mediated Survival Gene Expression Program in Primary Effusion Lymphoma. mBio. 11/2020; PubMed

Czech-Sioli M, Günther T, Therre M, Spohn M, Indenbirken D, Theiss J, Riethdorf S, Qi M, Alawi M, Wülbeck C, Fernandez-Cuesta I, Esmek F, Becker JC, Grundhoff A, Fischer N (2020). High-resolution analysis of Merkel Cell Polyomavirus in Merkel Cell Carcinoma reveals distinct integration patterns and suggests NHEJ and MMBIR as underlying mechanisms. PLoS Pathog. 16/2020; PubMed

McHugh D, Myburgh R, Caduff N, Spohn M, Kok YL, Keller CW, Murer A, Chatterjee B, Rühl J, Engelmann C, Chijioke O, Quast I, Shilaih M, Strouvelle VP, Neumann K, Menter T, Dirnhofer S, Lam JK, Hui KF, Bredl S, Schlaepfer E, Sorce S, Zbinden A, Capaul R, Lünemann JD, Aguzzi A, Chiang AK, Kempf W, Trkola A, Metzner KJ, Manz MG, Grundhoff A, Speck RF, Münz C (2020). EBV renders B cells susceptible to HIV-1 in humanized mice. Life Sci Alliance. 3/2020; PubMed

Astafyeva Y, Alawi M, Indenbirken D, Danso D, Grundhoff A, Hanelt D, Streit WR, Krohn I (2020). Draft Genome Sequence of the Green Alga Scenedesmus acuminatus SAG 38.81. Microbiol Resour Announc. 9/2020; PubMed

Gramolelli S, Elbasani E, Tuohinto K, Nurminen V, Günther T, Kallinen RE, Kaijalainen SP, Diaz R, Grundhoff A, Haglund C, Ziegelbauer JM, Pellinen T, Bower M, Francois M, Ojala PM (2020). Oncogenic Herpesvirus Engages Endothelial Transcription Factors SOX18 and PROX1 to Increase Viral Genome Copies and Virus Production. Cancer Res. 80/2020; PubMed

Robitaille A, Brancaccio RN, Dutta S, Rollison DE, Leja M, Fischer N, Grundhoff A, Gheit T, Tommasino M, Olivier M (2020). PVAmpliconFinder: a workflow for the identification of human papillomaviruses from high-throughput amplicon sequencing. BMC Bioinformatics. 21/2020; PubMed

Pfefferle S, Huang J, Nörz D, Indenbirken D, Lütgehetmann M, Oestereich L, Günther T, Grundhoff A, Aepfelbacher M, Fischer N (2020). Complete Genome Sequence of a SARS-CoV-2 Strain Isolated in Northern Germany. Microbiol Resour Announc. 9/2020; PubMed

Thiele S, Stanelle-Bertram S, Beck S, Kouassi NM, Zickler M, Müller M, Tuku B, Resa-Infante P, van Riel D, Alawi M, Günther T, Rother F, Hügel S, Reimering S, McHardy A, Grundhoff A, Brune W, Osterhaus A, Bader M, Hartmann E, Gabriel G (2020). Cellular Importin-α3 Expression Dynamics in the Lung Regulate Antiviral Response Pathways against Influenza A Virus Infection. Cell Rep. 31/2020; PubMed

Elbasani E, Gramolelli S, Günther T, Gabaev I, Grundhoff A, Ojala PM (2020). Kaposi's Sarcoma-Associated Herpesvirus Lytic Replication Is Independent of Anaphase-Promoting Complex Activity. J Virol. 94/2020; PubMed

Beck S, Zickler M, Pinho Dos Reis V, Günther T, Grundhoff A, Reilly PT, Mak TW, Stanelle-Bertram S, Gabriel G (2020). ANP32B Deficiency Protects Mice From Lethal Influenza A Virus Challenge by Dampening the Host Immune Response. Front Immunol. 11/2020; PubMed

Fröhlich J, Grundhoff A (2020). Epigenetic control in Kaposi sarcoma-associated herpesvirus infection and associated disease. Semin Immunopathol. 42/2020; PubMed

Siebels S, Czech-Sioli M, Spohn M, Schmidt C, Theiss J, Indenbirken D, Günther T, Grundhoff A, Fischer N (2020). Merkel Cell Polyomavirus DNA Replication Induces Senescence in Human Dermal Fibroblasts in a Kap1/Trim28-Dependent Manner. mBio. 11/2020; PubMed

Zapatka M, Borozan I, Brewer DS, Iskar M, Grundhoff A, Alawi M, Desai N, Sültmann H, Moch H, , Cooper CS, Eils R, Ferretti V, Lichter P, (2020). The landscape of viral associations in human cancers. Nat Genet. 52/2020; PubMed

Czech-Sioli M, Siebels S, Radau S, Zahedi RP, Schmidt C, Dobner T, Grundhoff A, Fischer N (2020). The Ubiquitin-Specific Protease Usp7, a Novel Merkel Cell Polyomavirus Large T-Antigen Interaction Partner, Modulates Viral DNA Replication. J Virol. 94/2020; PubMed

Alawi M, Burkhardt L, Indenbirken D, Reumann K, Christopeit M, Kröger N, Lütgehetmann M, Aepfelbacher M, Fischer N, Grundhoff A (2019). DAMIAN: an open source bioinformatics tool for fast, systematic and cohort based analysis of microorganisms in diagnostic samples. Sci Rep. 9/2019; PubMed

Günther T, Fröhlich J, Herrde C, Ohno S, Burkhardt L, Adler H, Grundhoff A (2019). A comparative epigenome analysis of gammaherpesviruses suggests cis-acting sequence features as critical mediators of rapid polycomb recruitment. PLoS Pathog. 15/2019; PubMed

Pich D, Mrozek-Gorska P, Bouvet M, Sugimoto A, Akidil E, Grundhoff A, Hamperl S, Ling PD, Hammerschmidt W (2019). First Days in the Life of Naive Human B Lymphocytes Infected with Epstein-Barr Virus. mBio. 10/2019; PubMed

Chemnitz J, Pieper D, Stich L, Schumacher U, Balabanov S, Spohn M, Grundhoff A, Steinkasserer A, Hauber J, Zinser E (2019). The acidic protein rich in leucines Anp32b is an immunomodulator of inflammation in mice. Sci Rep. 9/2019; PubMed

Bossler F, Kuhn BJ, Günther T, Kraemer SJ, Khalkar P, Adrian S, Lohrey C, Holzer A, Shimobayashi M, Dürst M, Mayer A, Rösl F, Grundhoff A, Krijgsveld J, Hoppe-Seyler K, Hoppe-Seyler F (2019). Repression of Human Papillomavirus Oncogene Expression under Hypoxia Is Mediated by PI3K/mTORC2/AKT Signaling. mBio. 10/2019; PubMed

Fux R, Arndt D, Langenmayer MC, Schwaiger J, Ferling H, Fischer N, Indenbirken D, Grundhoff A, Dölken L, Adamek M, Steinhagen D, Sutter G (2019). Piscine Orthoreovirus 3 Is Not the Causative Pathogen of Proliferative Darkening Syndrome (PDS) of Brown Trout (Salmo trutta fario). Viruses. 11/2019; PubMed

Neelagandan N, Gonnella G, Dang S, Janiesch PC, Miller KK, Küchler K, Marques RF, Indenbirken D, Alawi M, Grundhoff A, Kurtz S, Duncan KE (2019). TDP-43 enhances translation of specific mRNAs linked to neurodegenerative disease. Nucleic Acids Res. 47/2019; PubMed

Rubbenstroth D, Peus E, Schramm E, Kottmann D, Bartels H, McCowan C, Schulze C, Akimkin V, Fischer N, Wylezich C, Hlinak A, Spadinger A, Großmann E, Petersen H, Grundhoff A, Rautenschlein S, Teske L (2018). Identification of a novel clade of group A rotaviruses in fatally diseased domestic pigeons in Europe. Transbound Emerg Dis. 66/2019; PubMed

Chirayil R, Kincaid RP, Dahlke C, Kuny CV, Dälken N, Spohn M, Lawson B, Grundhoff A, Sullivan CS (2018). Identification of virus-encoded microRNAs in divergent Papillomaviruses. PLoS Pathog. 14/2018; PubMed

Speranza E, Ruibal P, Port JR, Feng F, Burkhardt L, Grundhoff A, Günther S, Oestereich L, Hiscox JA, Connor JH, Muñoz-Fontela C (2018). T-Cell Receptor Diversity and the Control of T-Cell Homeostasis Mark Ebola Virus Disease Survival in Humans. J Infect Dis. 218/2018; PubMed

Brancaccio RN, Robitaille A, Dutta S, Cuenin C, Santare D, Skenders G, Leja M, Fischer N, Giuliano AR, Rollison DE, Grundhoff A, Tommasino M, Gheit T (2018). Generation of a novel next-generation sequencing-based method for the isolation of new human papillomavirus types. Virology. 520/2018; PubMed

Fischer T, Spohn M, Olearo F, Zinser ME, Kasonta R, Stubbe HC, Rechtien A, Ly ML, Schmiedel S, Lohse AW, Grundhoff A, , Addo MM, Dahlke C (2018). Dynamic changes of circulating miRNAs induced by the Ebola virus vaccine VSV-EBOV. Vaccine. 36/2018; PubMed

Krohn-Molt I, Alawi M, Förstner KU, Wiegandt A, Burkhardt L, Indenbirken D, Thieß M, Grundhoff A, Kehr J, Tholey A, Streit WR (2017). Insights into Microalga and Bacteria Interactions of Selected Phycosphere Biofilms Using Metagenomic, Transcriptomic, and Proteomic Approaches. Front Microbiol. 8/2017; PubMed

Brancaccio RN, Robitaille A, Dutta S, Rollison DE, Fischer N, Grundhoff A, Tommasino M, Gheit T (2017). Complete Genome Sequence of a Novel Human Gammapapillomavirus Isolated from Skin. Genome Announc. 5/2017; PubMed

Günther T, Grundhoff A (2017). Epigenetic manipulation of host chromatin by Kaposi sarcoma-associated herpesvirus: a tumor-promoting factor? Curr Opin Virol. 26/2017; PubMed

McHugh D, Caduff N, Barros MHM, Rämer PC, Raykova A, Murer A, Landtwing V, Quast I, Styles CT, Spohn M, Fowotade A, Delecluse HJ, Papoudou-Bai A, Lee YM, Kim JM, Middeldorp J, Schulz TF, Cesarman E, Zbinden A, Capaul R, White RE, Allday MJ, Niedobitek G, Blackbourn DJ, Grundhoff A, Münz C (2017). Persistent KSHV Infection Increases EBV-Associated Tumor Formation In Vivo via Enhanced EBV Lytic Gene Expression. Cell Host Microbe. 22/2017; PubMed

Günther T, Haas L, Alawi M, Wohlsein P, Marks J, Grundhoff A, Becher P, Fischer N (2017). Recovery of the first full-length genome sequence of a parapoxvirus directly from a clinical sample. Sci Rep. 7/2017; PubMed

Knips J, Czech-Sioli M, Spohn M, Heiland M, Moll I, Grundhoff A, Schumacher U, Fischer N (2017). Spontaneous lung metastasis formation of human Merkel cell carcinoma cell lines transplanted into scid mice. Int J Cancer. 141/2017; PubMed

Coronado L, Liniger M, Muñoz-González S, Postel A, Pérez LJ, Pérez-Simó M, Perera CL, Frías-Lepoureau MT, Rosell R, Grundhoff A, Indenbirken D, Alawi M, Fischer N, Becher P, Ruggli N, Ganges L (2017). Novel poly-uridine insertion in the 3'UTR and E2 amino acid substitutions in a low virulent classical swine fever virus. Vet Microbiol. 201/2017; PubMed

Engels G, Hierweger AM, Hoffmann J, Thieme R, Thiele S, Bertram S, Dreier C, Resa-Infante P, Jacobsen H, Thiele K, Alawi M, Indenbirken D, Grundhoff A, Siebels S, Fischer N, Stojanovska V, Muzzio D, Jensen F, Karimi K, Mittrücker HW, Arck PC, Gabriel G (2017). Pregnancy-Related Immune Adaptation Promotes the Emergence of Highly Virulent H1N1 Influenza Virus Strains in Allogenically Pregnant Mice. Cell Host Microbe. 21/2017; PubMed

Xie W, Nagarajan S, Baumgart SJ, Kosinsky RL, Najafova Z, Kari V, Hennion M, Indenbirken D, Bonn S, Grundhoff A, Wegwitz F, Mansouri A, Johnsen SA (2017). RNF40 regulates gene expression in an epigenetic context-dependent manner. Genome Biol. 18/2017; PubMed

Todt D, Schlevogt B, Deterding K, Grundhoff A, Manns MP, Wedemeyer H, Fischer N, Cornberg M, Steinmann E (2017). Successful retreatment of a patient with chronic hepatitis C genotype 2k/1b virus with ombitasvir/paritaprevir/ritonavir plus dasabuvir. J Antimicrob Chemother. 72/2017; PubMed

Nagarajan S, Bedi U, Budida A, Hamdan FH, Mishra VK, Najafova Z, Xie W, Alawi M, Indenbirken D, Knapp S, Chiang CM, Grundhoff A, Kari V, Scheel CH, Wegwitz F, Johnsen SA (2017). BRD4 promotes p63 and GRHL3 expression downstream of FOXO in mammary epithelial cells. Nucleic Acids Res. 45/2017; PubMed

Both A, Huang J, Kaase M, Hezel J, Wertheimer D, Fenner I, Günther T, Grundhoff A, Büttner H, Aepfelbacher M, Rohde H, Hentschke M (2016). First report of Escherichia coli co-producing NDM-1 and OXA-232. Diagn Microbiol Infect Dis. 86/2016; PubMed

Fischer S, Cornils K, Speiseder T, Badbaran A, Reimer R, Indenbirken D, Grundhoff A, Brunswig-Spickenheier B, Alawi M, Lange C (2016). Indication of Horizontal DNA Gene Transfer by Extracellular Vesicles. PLoS One. 11/2016; PubMed

Neumann F, Czech-Sioli M, Dobner T, Grundhoff A, Schreiner S, Fischer N (2016). Replication of Merkel cell polyomavirus induces reorganization of promyelocytic leukemia nuclear bodies. J Gen Virol. 97/2016; PubMed

Berneking L, Schnapp M, Rumm A, Trasak C, Ruckdeschel K, Alawi M, Grundhoff A, Kikhney AG, Koch-Nolte F, Buck F, Perbandt M, Betzel C, Svergun DI, Hentschke M, Aepfelbacher M (2016). Immunosuppressive Yersinia Effector YopM Binds DEAD Box Helicase DDX3 to Control Ribosomal S6 Kinase in the Nucleus of Host Cells. PLoS Pathog. 12/2016; PubMed

Postel A, Hansmann F, Baechlein C, Fischer N, Alawi M, Grundhoff A, Derking S, Tenhündfeld J, Pfankuche VM, Herder V, Baumgärtner W, Wendt M, Becher P (2016). Presence of atypical porcine pestivirus (APPV) genomes in newborn piglets correlates with congenital tremor. Sci Rep. 6/2016; PubMed

Güllert S, Fischer MA, Turaev D, Noebauer B, Ilmberger N, Wemheuer B, Alawi M, Rattei T, Daniel R, Schmitz RA, Grundhoff A, Streit WR (2016). Deep metagenome and metatranscriptome analyses of microbial communities affiliated with an industrial biogas fermenter, a cow rumen, and elephant feces reveal major differences in carbohydrate hydrolysis strategies. Biotechnol Biofuels. 9/2016; PubMed

Hossan T, Nagarajan S, Baumgart SJ, Xie W, Magallanes RT, Hernandez C, Chiaroni PM, Indenbirken D, Spitzner M, Thomas-Chollier M, Grade M, Thieffry D, Grundhoff A, Wegwitz F, Johnsen SA (2016). Histone Chaperone SSRP1 is Essential for Wnt Signaling Pathway Activity During Osteoblast Differentiation. Stem Cells. 34/2016; PubMed

Schieferdecker A, Oberle A, Thiele B, Hofmann F, Göthel M, Miethe S, Hust M, Braig F, Voigt M, von Pein UM, Koch-Nolte F, Haag F, Alawi M, Indenbirken D, Grundhoff A, Bokemeyer C, Bacher U, Kröger N, Binder M (2016). A transplant "immunome" screening platform defines a targetable epitope fingerprint of multiple myeloma. Blood. 127/2016; PubMed

Westblade LF, van Belkum A, Grundhoff A, Weinstock GM, Pamer EG, Pallen MJ, Dunne WM (2016). Role of Clinicogenomics in Infectious Disease Diagnostics and Public Health Microbiology. J Clin Microbiol. 54/2016; PubMed

Schommartz T, Loroch S, Alawi M, Grundhoff A, Sickmann A, Brune W (2016). Functional Dissection of an Alternatively Spliced Herpesvirus Gene by Splice Site Mutagenesis. J Virol. 90/2016; PubMed

Karpinski J, Hauber I, Chemnitz J, Schäfer C, Paszkowski-Rogacz M, Chakraborty D, Beschorner N, Hofmann-Sieber H, Lange UC, Grundhoff A, Hackmann K, Schrock E, Abi-Ghanem J, Pisabarro MT, Surendranath V, Schambach A, Lindner C, van Lunzen J, Hauber J, Buchholz F (2016). Directed evolution of a recombinase that excises the provirus of most HIV-1 primary isolates with high specificity. Nat Biotechnol. 34/2016; PubMed

Günther T, Theiss JM, Fischer N, Grundhoff A (2016). Investigation of Viral and Host Chromatin by ChIP-PCR or ChIP-Seq Analysis. Curr Protoc Microbiol. 40/2016; PubMed

Christopeit M, Grundhoff A, Rohde H, Belmar-Campos C, Grzyska U, Fiehler J, Wolschke C, Ayuk F, Kröger N, Fischer N (2016). Suspected encephalitis with Candida tropicalis and Fusarium detected by unbiased RNA sequencing. Ann Hematol. 95/2016; PubMed

Grundhoff A, Fischer N (2015). Merkel cell polyomavirus, a highly prevalent virus with tumorigenic potential. Curr Opin Virol. 14/2015; PubMed

Neumann F, Czech-Sioli M, Grundhoff A, Fischer N (2015). In Vitro Replication Assay for Merkel Cell Polyomavirus (MCPyV). Curr Protoc Microbiol. 38/2015; PubMed

Theiss JM, Günther T, Alawi M, Neumann F, Tessmer U, Fischer N, Grundhoff A (2015). A Comprehensive Analysis of Replicating Merkel Cell Polyomavirus Genomes Delineates the Viral Transcription Program and Suggests a Role for mcv-miR-M1 in Episomal Persistence. PLoS Pathog. 11/2015; PubMed

Braig F, März M, Schieferdecker A, Schulte A, Voigt M, Stein A, Grob T, Alawi M, Indenbirken D, Kriegs M, Engel E, Vanhoefer U, Grundhoff A, Loges S, Riecken K, Fehse B, Bokemeyer C, Binder M (2015). Epidermal growth factor receptor mutation mediates cross-resistance to panitumumab and cetuximab in gastrointestinal cancer. Oncotarget. 6/2015; PubMed

Fischer N, Indenbirken D, Meyer T, Lütgehetmann M, Lellek H, Spohn M, Aepfelbacher M, Alawi M, Grundhoff A (2015). Evaluation of Unbiased Next-Generation Sequencing of RNA (RNA-seq) as a Diagnostic Method in Influenza Virus-Positive Respiratory Samples. J Clin Microbiol. 53/2015; PubMed

Baechlein C, Fischer N, Grundhoff A, Alawi M, Indenbirken D, Postel A, Baron AL, Offinger J, Becker K, Beineke A, Rehage J, Becher P (2015). Identification of a Novel Hepacivirus in Domestic Cattle from Germany. J Virol. 89/2015; PubMed

Corman VM, Grundhoff A, Baechlein C, Fischer N, Gmyl A, Wollny R, Dei D, Ritz D, Binger T, Adankwah E, Marfo KS, Annison L, Annan A, Adu-Sarkodie Y, Oppong S, Becher P, Drosten C, Drexler JF (2015). Highly divergent hepaciviruses from African cattle. J Virol. 89/2015; PubMed

Kati S, Hage E, Mynarek M, Ganzenmueller T, Indenbirken D, Grundhoff A, Schulz TF (2015). Generation of high-titre virus stocks using BrK.219, a B-cell line infected stably with recombinant Kaposi's sarcoma-associated herpesvirus. J Virol Methods. 217/2015; PubMed

Bruce AG, Thouless ME, Haines AS, Pallen MJ, Grundhoff A, Rose TM (2015). Complete genome sequence of Pig-tailed macaque rhadinovirus 2 and its evolutionary relationship with rhesus macaque rhadinovirus and human herpesvirus 8/Kaposi's sarcoma-associated herpesvirus. J Virol. 89/2015; PubMed

Karimova M, Beschorner N, Dammermann W, Chemnitz J, Indenbirken D, Bockmann JH, Grundhoff A, Lüth S, Buchholz F, Schulze zur Wiesch J, Hauber J (2015). CRISPR/Cas9 nickase-mediated disruption of hepatitis B virus open reading frame S and X. Sci Rep. 5/2015; PubMed

Ilmberger N, Güllert S, Dannenberg J, Rabausch U, Torres J, Wemheuer B, Alawi M, Poehlein A, Chow J, Turaev D, Rattei T, Schmeisser C, Salomon J, Olsen PB, Daniel R, Grundhoff A, Borchert MS, Streit WR (2014). A comparative metagenome survey of the fecal microbiota of a breast- and a plant-fed Asian elephant reveals an unexpectedly high diversity of glycoside hydrolase family enzymes. PLoS One. 9/2014; PubMed

Günther T, Schreiner S, Dobner T, Tessmer U, Grundhoff A (2014). Influence of ND10 components on epigenetic determinants of early KSHV latency establishment. PLoS Pathog. 10/2014; PubMed

Thiele B, Kloster M, Alawi M, Indenbirken D, Trepel M, Grundhoff A, Binder M (2014). Next-generation sequencing of peripheral B-lineage cells pinpoints the circulating clonotypic cell pool in multiple myeloma. Blood. 123/2014; PubMed

Nagarajan S, Hossan T, Alawi M, Najafova Z, Indenbirken D, Bedi U, Taipaleenmäki H, Ben-Batalla I, Scheller M, Loges S, Knapp S, Hesse E, Chiang CM, Grundhoff A, Johnsen SA (2014). Bromodomain protein BRD4 is required for estrogen receptor-dependent enhancer activation and gene transcription. Cell Rep. 8/2014; PubMed

Niebuhr B, Kriebitzsch N, Fischer M, Behrens K, Günther T, Alawi M, Bergholz U, Müller U, Roscher S, Ziegler M, Buchholz F, Grundhoff A, Stocking C (2013). Runx1 is essential at two stages of early murine B-cell development. Blood. 122/2013; PubMed

Hauber I, Hofmann-Sieber H, Chemnitz J, Dubrau D, Chusainow J, Stucka R, Hartjen P, Schambach A, Ziegler P, Hackmann K, Schröck E, Schumacher U, Lindner C, Grundhoff A, Baum C, Manz MG, Buchholz F, Hauber J (2013). Highly significant antiviral activity of HIV-1 LTR-specific tre-recombinase in humanized mice. PLoS Pathog. 9/2013; PubMed

Vereide DT, Seto E, Chiu YF, Hayes M, Tagawa T, Grundhoff A, Hammerschmidt W, Sugden B (2013). Epstein-Barr virus maintains lymphomas via its miRNAs. Oncogene. 33/2014; PubMed

Dahlke C, Maul K, Christalla T, Walz N, Schult P, Stocking C, Grundhoff A (2012). A microRNA encoded by Kaposi sarcoma-associated herpesvirus promotes B-cell expansion in vivo. PLoS One. 7/2012; PubMed

Mariyanna L, Priyadarshini P, Hofmann-Sieber H, Krepstakies M, Walz N, Grundhoff A, Buchholz F, Hildt E, Hauber J (2012). Excision of HIV-1 proviral DNA by recombinant cell permeable tre-recombinase. PLoS One. 7/2012; PubMed

Grundhoff A (2011). Computational prediction of viral miRNAs. Methods Mol Biol. 721/2011; PubMed

Grundhoff A, Sullivan CS (2011). Virus-encoded microRNAs. Virology. 411/2011; PubMed

Günther T, Grundhoff A (2010). The epigenetic landscape of latent Kaposi sarcoma-associated herpesvirus genomes. PLoS Pathog. 6/2010; PubMed

Walz N, Christalla T, Tessmer U, Grundhoff A (2009). A global analysis of evolutionary conservation among known and predicted gammaherpesvirus microRNAs. J Virol. 84/2010; PubMed

Grundhoff A, Sullivan CS, Ganem D (2006). A combined computational and microarray-based approach identifies novel microRNAs encoded by human gamma-herpesviruses. RNA. 12/2006; PubMed