Mitarbeiterinnen und Mitarbeiter

Dhillon A, Persson BD, Volkov AN, Sülzen H, Kádek A, Pompach P, Kereïche S, Lepšík M, Danskog K, Uetrecht C, Arnberg N, Zoll S (2024). Structural insights into the interaction between adenovirus C5 hexon and human lactoferrin. J Virol. 98/2024; PubMed

Hagan MF, Zandi R, Uetrecht C (2024). Overview of the 2023 Physical Virology Gordon Research Conference-Viruses at Multiple Levels of Complexity. Viruses. 16/2024; PubMed

Brodmerkel MN, Thiede L, De Santis E, Uetrecht C, Caleman C, Marklund EG (2024). Collision induced unfolding and molecular dynamics simulations of norovirus capsid dimers reveal strain-specific stability profiles. Phys Chem Chem Phys. 26/2024; PubMed

Sänger L, Williams HM, Yu D, Vogel D, Kosinski J, Rosenthal M, Uetrecht C (2023). RNA to Rule Them All: Critical Steps in Lassa Virus Ribonucleoparticle Assembly and Recruitment. J Am Chem Soc. 145/2023; PubMed

Feng Y, Pogan R, Thiede L, Müller-Guhl J, Uetrecht C, Roos WH (2023). Fucose Binding Cancels out Mechanical Differences between Distinct Human Noroviruses. Viruses. 15/2023; PubMed

Soh TK, Pfefferle S, Wurr S, von Possel R, Oestereich L, Rieger T, Uetrecht C, Rosenthal M, Bosse JB (2023). A validated protocol to UV-inactivate SARS-CoV-2 and herpesvirus-infected cells. PLoS One. 18/2023; PubMed

Kierspel T, Kadek A, Barran P, Bellina B, Bijedic A, Brodmerkel MN, Commandeur J, Caleman C, Damjanović T, Dawod I, De Santis E, Lekkas A, Lorenzen K, Morillo LL, Mandl T, Marklund EG, Papanastasiou D, Ramakers LAI, Schweikhard L, Simke F, Sinelnikova A, Smyrnakis A, Timneanu N, Uetrecht C, (2023). Coherent diffractive imaging of proteins and viral capsids: simulating MS SPIDOC. Anal Bioanal Chem. 415/2023; PubMed

Brodmerkel MN, De Santis E, Uetrecht C, Caleman C, Marklund EG (2022). Stability and conformational memory of electrosprayed and rehydrated bacteriophage MS2 virus coat proteins. Curr Res Struct Biol. 4/2022; PubMed

Shukla S, Komarek J, Novakova Z, Nedvedova J, Ustinova K, Vankova P, Kadek A, Uetrecht C, Mertens H, Barinka C (2022). In-solution structure and oligomerization of human histone deacetylase 6 - an integrative approach. FEBS J. 290/2023; PubMed

Creutznacher R, Maass T, Veselkova B, Ssebyatika G, Krey T, Empting M, Tautz N, Frank M, Kölbel K, Uetrecht C, Peters T (2022). NMR Experiments Provide Insights into Ligand-Binding to the SARS-CoV-2 Spike Protein Receptor-Binding Domain. J Am Chem Soc. 144/2022; PubMed

Creutznacher R, Maass T, Dülfer J, Feldmann C, Hartmann V, Lane MS, Knickmann J, Westermann LT, Thiede L, Smith TJ, Uetrecht C, Mallagaray A, Waudby CA, Taube S, Peters T (2022). Distinct dissociation rates of murine and human norovirus P-domain dimers suggest a role of dimer stability in virus-host interactions. Commun Biol. 5/2022; PubMed

Kopicki JD, Saikia A, Niebling S, Günther C, Anjanappa R, Garcia-Alai M, Springer S, Uetrecht C (2022). Opening opportunities for Kd determination and screening of MHC peptide complexes. Commun Biol. 5/2022; PubMed

Dirscherl C, Löchte S, Hein Z, Kopicki JD, Harders AR, Linden N, Karner A, Preiner J, Weghuber J, Garcia-Alai M, Uetrecht C, Zacharias M, Piehler J, Lanzerstorfer P, Springer S (2022). Dissociation of β2m from MHC class I triggers formation of noncovalent transient heavy chain dimers. J Cell Sci. 135/2022; PubMed

Maass T, Westermann LT, Creutznacher R, Mallagaray A, Dülfer J, Uetrecht C, Peters T (2022). Assignment of Ala, Ile, LeuproS, Met, and ValproS methyl groups of the protruding domain of murine norovirus capsid protein VP1 using methyl-methyl NOEs, site directed mutagenesis, and pseudocontact shifts. Biomol NMR Assign. 16/2022; PubMed

Peters T, Creutznacher R, Maass T, Mallagaray A, Ogrissek P, Taube S, Thiede L, Uetrecht C (2022). Norovirus-glycan interactions - how strong are they really? Biochem Soc Trans. 50/2022; PubMed

Konietzny A, Grendel J, Kadek A, Bucher M, Han Y, Hertrich N, Dekkers DHW, Demmers JAA, Grünewald K, Uetrecht C, Mikhaylova M (2021). Caldendrin and myosin V regulate synaptic spine apparatus localization via ER stabilization in dendritic spines. EMBO J. 41/2022; PubMed

Kadek A, Lorenzen K, Uetrecht C, (2021). In a flash of light: X-ray free electron lasers meet native mass spectrometry. Drug Discov Today Technol. 39/2021; PubMed

Yan H, Lockhauserbäumer J, Szekeres GP, Mallagaray A, Creutznacher R, Taube S, Peters T, Pagel K, Uetrecht C (2021). Protein Secondary Structure Affects Glycan Clustering in Native Mass Spectrometry. Life (Basel). 11/2021; PubMed

Simanjuntak Y, Schamoni-Kast K, Grün A, Uetrecht C, Scaturro P (2021). Top-Down and Bottom-Up Proteomics Methods to Study RNA Virus Biology. Viruses. 13/2021; PubMed

Dülfer J, Yan H, Brodmerkel MN, Creutznacher R, Mallagaray A, Peters T, Caleman C, Marklund EG, Uetrecht C (2021). Glycan-Induced Protein Dynamics in Human Norovirus P Dimers Depend on Virus Strain and Deamidation Status. Molecules. 26/2021; PubMed

Han H, Round E, Schubert R, Gül Y, Makroczyová J, Meza D, Heuser P, Aepfelbacher M, Barák I, Betzel C, Fromme P, Kursula I, Nissen P, Tereschenko E, Schulz J, Uetrecht C, Ulicný J, Wilmanns M, Hajdu J, Lamzin VS, Lorenzen K (2021). The XBI BioLab for life science experiments at the European XFEL. J Appl Crystallogr. 54/2021; PubMed

Günther S, Reinke PYA, Fernández-García Y, Lieske J, Lane TJ, Ginn HM, Koua FHM, Ehrt C, Ewert W, Oberthuer D, Yefanov O, Meier S, Lorenzen K, Krichel B, Kopicki JD, Gelisio L, Brehm W, Dunkel I, Seychell B, Gieseler H, Norton-Baker B, Escudero-Pérez B, Domaracky M, Saouane S, Tolstikova A, White TA, Hänle A, Groessler M, Fleckenstein H, Trost F, Galchenkova M, Gevorkov Y, Li C, Awel S, Peck A, Barthelmess M, Schlünzen F, Lourdu Xavier P, Werner N, Andaleeb H, Ullah N, Falke S, Srinivasan V, França BA, Schwinzer M, Brognaro H, Rogers C, Melo D, Zaitseva-Kinneberg JI, Knoska J, Peña-Murillo GE, Mashhour AR, Hennicke V, Fischer P, Hakanpää J, Meyer J, Gribbon P, Ellinger B, Kuzikov M, Wolf M, Beccari AR, Bourenkov G, von Stetten D, Pompidor G, Bento I, Panneerselvam S, Karpics I, Schneider TR, Garcia-Alai MM, Niebling S, Günther C, Schmidt C, Schubert R, Han H, Boger J, Monteiro DCF, Zhang L, Sun X, Pletzer-Zelgert J, Wollenhaupt J, Feiler CG, Weiss MS, Schulz EC, Mehrabi P, Karničar K, Usenik A, Loboda J, Tidow H, Chari A, Hilgenfeld R, Uetrecht C, Cox R, Zaliani A, Beck T, Rarey M, Günther S, Turk D, Hinrichs W, Chapman HN, Pearson AR, Betzel C, Meents A (2021). X-ray screening identifies active site and allosteric inhibitors of SARS-CoV-2 main protease. Science. 372/2021; PubMed

Krichel B, Bylapudi G, Schmidt C, Blanchet C, Schubert R, Brings L, Koehler M, Zenobi R, Svergun D, Lorenzen K, Madhugiri R, Ziebuhr J, Uetrecht C (2021). Hallmarks of Alpha- and Betacoronavirus non-structural protein 7+8 complexes. Sci Adv. 7/2021; PubMed

Pogan R, Weiss VU, Bond K, Dülfer J, Krisp C, Lyktey N, Müller-Guhl J, Zoratto S, Allmaier G, Jarrold MF, Muñoz-Fontela C, Schlüter H, Uetrecht C (2020). N-terminal VP1 Truncations Favor T = 1 Norovirus-Like Particles. Vaccines (Basel). 9/2020; PubMed

Krichel B, Bylapudi G, Schmidt C, Blanchet C, Schubert R, Brings L, Koehler M, Zenobi R, Svergun D, Lorenzen K, Madhugiri R, Ziebuhr J, Uetrecht C (2020). Hallmarks of Alpha- and Betacoronavirus non-structural protein 7+8 complexes. bioRxiv. 2020 Oct 07; PubMed

Schulz EC, Henderson SR, Illarionov B, Crosskey T, Southall SM, Krichel B, Uetrecht C, Fischer M, Wilmanns M (2020). The crystal structure of mycobacterial epoxide hydrolase A. Sci Rep. 10/2020; PubMed

Horstmann JA, Lunelli M, Cazzola H, Heidemann J, Kühne C, Steffen P, Szefs S, Rossi C, Lokareddy RK, Wang C, Lemaire L, Hughes KT, Uetrecht C, Schlüter H, Grassl GA, Stradal TEB, Rossez Y, Kolbe M, Erhardt M (2020). Methylation of Salmonella Typhimurium flagella promotes bacterial adhesion and host cell invasion. Nat Commun. 11/2020; PubMed

Anjanappa R, Garcia-Alai M, Kopicki JD, Lockhauserbäumer J, Aboelmagd M, Hinrichs J, Nemtanu IM, Uetrecht C, Zacharias M, Springer S, Meijers R (2020). Structures of peptide-free and partially loaded MHC class I molecules reveal mechanisms of peptide selection. Nat Commun. 11/2020; PubMed

Krichel B, Falke S, Hilgenfeld R, Redecke L, Uetrecht C (2020). Processing of the SARS-CoV pp1a/ab nsp7-10 region. Biochem J. 477/2020; PubMed

Heidemann J, Kölbel K, Konijnenberg A, Van Dyck J, Garcia-Alai M, Meijers R, Sobott F, Uetrecht C (2019). Further insights from structural mass spectrometry into endocytosis adaptor protein assemblies. Int J Mass Spectrom. 447/2020; PubMed

Dülfer J, Kadek A, Kopicki JD, Krichel B, Uetrecht C (2019). Structural mass spectrometry goes viral. Adv Virus Res. 105/2019; PubMed

Bernal I, Römermann J, Flacht L, Lunelli M, Uetrecht C, Kolbe M (2019). Structural analysis of ligand-bound states of the Salmonella type III secretion system ATPase InvC. Protein Sci. 28/2019; PubMed

Bernal I, Börnicke J, Heidemann J, Svergun D, Horstmann JA, Erhardt M, Tuukkanen A, Uetrecht C, Kolbe M (2019). Molecular Organization of Soluble Type III Secretion System Sorting Platform Complexes. J Mol Biol. 431/2019; PubMed

Weiss VU, Pogan R, Zoratto S, Bond KM, Boulanger P, Jarrold MF, Lyktey N, Pahl D, Puffler N, Schelhaas M, Selivanovitch E, Uetrecht C, Allmaier G (2019). Virus-like particle size and molecular weight/mass determination applying gas-phase electrophoresis (native nES GEMMA). Anal Bioanal Chem. 411/2019; PubMed

Uetrecht C, Lorenzen K, Kitel M, Heidemann J, Robinson Spencer JH, Schlüter H, Schulz J (2019). Native mass spectrometry provides sufficient ion flux for XFEL single-particle imaging. J Synchrotron Radiat. 26/2019; PubMed

Mallagaray A, Creutznacher R, Dülfer J, Mayer PHO, Grimm LL, Orduña JM, Trabjerg E, Stehle T, Rand KD, Blaum BS, Uetrecht C, Peters T (2019). A post-translational modification of human Norovirus capsid protein attenuates glycan binding. Nat Commun. 10/2019; PubMed

Zaitsev-Doyle JJ, Puchert A, Pfeifer Y, Yan H, Yorke BA, Müller-Werkmeister HM, Uetrecht C, Rehbein J, Huse N, Pearson AR, Sans M (2019). Synthesis and characterisation of α-carboxynitrobenzyl photocaged l-aspartates for applications in time-resolved structural biology. RSC Adv. 9/2019; PubMed

Kesgin-Schaefer S, Heidemann J, Puchert A, Koelbel K, Yorke BA, Huse N, Pearson AR, Uetrecht C, Tidow H (2019). Crystal structure of a domain-swapped photoactivatable sfGFP variant provides evidence for GFP folding pathway. FEBS J. 286/2019; PubMed

Nitsche J, Josts I, Heidemann J, Mertens HD, Maric S, Moulin M, Haertlein M, Busch S, Forsyth VT, Svergun DI, Uetrecht C, Tidow H (2018). Structural basis for activation of plasma-membrane Ca2+-ATPase by calmodulin. Commun Biol. 1/2018; PubMed

Holm T, Kopicki JD, Busch C, Olschewski S, Rosenthal M, Uetrecht C, Günther S, Reindl S (2018). Biochemical and structural studies reveal differences and commonalities among cap-snatching endonucleases from segmented negative-strand RNA viruses. J Biol Chem. 293/2018; PubMed

Bücher KS, Yan H, Creutznacher R, Ruoff K, Mallagaray A, Grafmüller A, Dirks JS, Kilic T, Weickert S, Rubailo A, Drescher M, Schmidt S, Hansman G, Peters T, Uetrecht C, Hartmann L (2018). Fucose-Functionalized Precision Glycomacromolecules Targeting Human Norovirus Capsid Protein. Biomacromolecules. 19/2018; PubMed

Pogan R, Dülfer J, Uetrecht C (2018). Norovirus assembly and stability. Curr Opin Virol. 31/2018; PubMed

Garcia-Alai MM, Heidemann J, Skruzny M, Gieras A, Mertens HDT, Svergun DI, Kaksonen M, Uetrecht C, Meijers R (2018). Epsin and Sla2 form assemblies through phospholipid interfaces. Nat Commun. 9/2018; PubMed

Wegener H, Mallagaray Á, Schöne T, Peters T, Lockhauserbäumer J, Yan H, Uetrecht C, Hansman GS, Taube S (2017). Human norovirus GII.4(MI001) P dimer binds fucosylated and sialylated carbohydrates. Glycobiology. 27/2017; PubMed

Shin HC, Deterra D, Park J, Kim H, Nishikiori M, Uetrecht C, Ahlquist PG, Arbulu M, Blick RH (2017). Ultra-high mass multimer analysis of protein-1a capping domains by a silicon nanomembrane detector. J Proteomics. 175/2018; PubMed

Szameit K, Berg K, Kruspe S, Valentini E, Magbanua E, Kwiatkowski M, Chauvot de Beauchêne I, Krichel B, Schamoni K, Uetrecht C, Svergun DI, Schlüter H, Zacharias M, Hahn U (2016). Structure and target interaction of a G-quadruplex RNA-aptamer. RNA Biol. 13/2016; PubMed

Dunne M, Leicht S, Krichel B, Mertens HD, Thompson A, Krijgsveld J, Svergun DI, Gómez-Torres N, Garde S, Uetrecht C, Narbad A, Mayer MJ, Meijers R (2015). Crystal Structure of the CTP1L Endolysin Reveals How Its Activity Is Regulated by a Secondary Translation Product. J Biol Chem. 291/2016; PubMed

Mallagaray A, Lockhauserbäumer J, Hansman G, Uetrecht C, Peters T (2015). Attachment of norovirus to histo blood group antigens: a cooperative multistep process. Angew Chem Int Ed Engl. 54/2015; PubMed