Mitarbeiterinnen und Mitarbeiter

Pujantell M, Altfeld M (2026). Sex-Specific Factors Influencing HIV Infection. Immunol Rev. 338/2026; PubMed

Skenteris NT, Luttermann E, Nair S, Evangelakos I, Pujantell M, Eggers M, Hausmann F, Bérouti M, Padoan B, Flomm FJ, Claussen JM, Grünhagel B, Salfelder A, Beifuss B, Biskup S, Blümke P, Rading K, Hildebrandt H, Matschl U, Giesemann-Jansen S, Hennesen J, Nikolaev VO, Kutsche M, Kubisch C, Koch-Nolte F, Tomas NM, Tolosa E, Lütgehetmann M, Stahl FR, Hornung V, Bunders MJ, Schlein C, Topf M, Kötter I, Altfeld M (2026). Structural modeling and functional characterization of a novel gain-of-function TLR8 variant causing severe inflammatory syndrome. JCI Insight. 11/2026; PubMed

Post S, Zamzamy M, Benthien L, Rueschpler L, Ip WH, Hahlin E, Kühn S, Conze C, Hoelzemer A, Dobner T, Arnberg N, Altfeld M, Schloer S (2026). Acid sphingomyelinase is an age-dependent host cell factor for adenovirus entry and a pharmacological target for synergistic combination therapy with brincidofovir. Biomed Pharmacother. 201/2026; PubMed

Reinsberg, F., Schiering, K., Lingstaedt, M. G., Mensching, L., Adiba, M., Kraus, T. V., Engler, J. B., Liebold, I., Bosurgi, L., Schloer, S., Altfeld, M., Friese, M. A., Krasemann, S., Lange, U. C., Garcia-Beltran, W. F. & Hoelzemer, A. (2026). HIV-1 promotes cell-to-cell interactions enabling spread from CD4+ T cells to microglia bioRxiv. URI

Bertrand L, Nelde A, Ramirez BC, Hatin I, Arbes H, François P, Demais S, Labaronne E, Decimo D, Guiguettaz L, Grégoire S, Bet A, Beauclair G, Gross A, Ziegler MC, Pereira M, Jeger-Madiot R, Verdier Y, Vinh J, Cardinaud S, Graff-Dubois S, Esclatine A, Gouttefangeas C, Altfeld M, Hocqueloux L, Samri A, Autran B, Lambotte O, Rammensee HG, Ricci EP, Walz J, Namy O, Moris A (2025). Unveiling conserved HIV-1 open reading frames encoding T cell antigens using ribosome profiling. Nat Commun. 16/2025; PubMed

Baiyegunhi OO, Mthembu K, Reuschl A-K, Ojwach D, Farinre O, Maimela M, Balinda S, Price M, Bunders MJ, Altfeld M, Jolly C, Mann J, Ndung'u T (2025). HIV-1 Gag-protease-driven replicative capacity influences T-cell metabolism, cytokine induction, and viral cell-to-cell spread. mBio. 2025 Feb 25; PubMed

Bertrand L, Nelde A, Ramirez BC, Hatin I, Arbes H, François P, Demais S, Labaronne E, Decimo D, Guiguettaz L, Grégoire S, Bet A, Beauclair G, Gross A, Ziegler MC, Pereira M, Jeger-Madiot R, Verdier Y, Vinh J, Cardinaud S, Graff-Dubois S, Esclatine A, Gouttefangeas C, Altfeld M, Hocqueloux L, Samri A, Autran B, Lambotte O, Rammensee HG, Ricci EP, Walz J, Namy O, Moris A (2025). Author Correction: Unveiling conserved HIV-1 open reading frames encoding T cell antigens using ribosome profiling. Nat Commun. 16/2025; PubMed

Henze L, Will N, Lee D, Haas V, Casar C, Meyer J, Stein S, Mangler F, Steinmann S, Poch T, Krause J, Fuss J, Schröder J, Kulle AE, Holterhus PM, Bonn S, Altfeld M, Huber S, Lohse AW, Schwinge D, Schramm C (2025). Testosterone affects female CD4+ T cells in healthy individuals and autoimmune liver diseases. JCI Insight. 10/2025; PubMed

Schloer S, Hennesen J, Rueschpler L, Zamzamy M, Flomm F, Ip WH, Pirosu A, Dobner T, Altfeld M (2025). The host cell factor DDX3 mediates sex dimorphism in the IFNα response of plasmacytoid dendritic cells upon TLR activation. Pharmacol Res. 2025 May 10; PubMed

Mensching L, Beiersdorfer M, Schloer S, Köllmann S, Reinsberg F, Padoan B, Fittje P, Trenkner T, Zaayenga A, Martrus G, Almahfoud M, Stürzel CM, Sauter D, Kirchhoff F, Schulze Zur Wiesch J, Altfeld M, Garcia-Beltran WF, Hoelzemer A (2025). HIV-1 infection of macrophages differentially primes NK-cell cytotoxicity and proinflammatory cytokine production. iScience. 28/2025; PubMed

van Leeuwen R, Barré-Sinoussi F, Müller-Trutwin M, Sáez-Cirión A, Nijhuis M, Lewin SR, Ndung'u T, Riako-Anam F, Warren M, Sikazwe I, Poniatowski B, Grinsztejn B, Kityo C, Davis M, Søgaard OS, Altfeld M, Martinez-Picado J, Vandekerckhove L, Gramatica A, Sok D, Collins S, Yazdanpanah Y (2025). The imperative for increased investment for an HIV cure. Lancet HIV. 2025 Jul 22; PubMed

Schloer S, Hennesen J, Rueschpler L, Zamzamy M, Flomm F, Skenteris NT, Ip WH, Pirosu A, Dobner T, Altfeld M (2025). Corrigendum to "The host cell factor DDX3 mediates sex dimorphism in the IFNα response of plasmacytoid dendritic cells upon TLR activation" [Pharmacol. Res. 216(June) (2025) 107764]. Pharmacol Res. 2025 Aug 01; PubMed

Altfeld M, Consiglio C, Darragh D, Ingersoll M, O'Farrelly C, Pecht T, Shay T, Soares H (2025). The Essential Integration of Sex and Gender in Immunological Research. Immunol Lett. 2025 Oct 09; PubMed

Zamzamy M, Post S, Ip WH, Hahlin E, Kühn S, Pirosu A, Conze C, Baumdick M, Bunders MJ, Zecher BF, Hoelzemer A, Linder S, Arnberg N, Dobner T, Altfeld M, Schloer S (2025). Synergistic antiviral activity against human adenovirus through combination of itraconazole and brincidofovir. Br J Pharmacol. 2025 Nov 28; PubMed

Hoelzemer, A., Trenkner, T., Brias, S., Kraus, T., Adiba, M., Nolan, K., Beiersdorfer, M., Vollmers, S., Schäfer, G., Stecher, M., Sauer, G., Behrens, G., Lehmann, C., Meurer, A., Pauli, R., Postel, N., Marseres, G., Sauter, J., Schmidt, A., Roider, J., Scholten, S., Voit, F., Stephan, C., Wolf, E., Schloer, S., Wuen, C., Degen, O., Addo, M., Lohse, A., Schulze zur Wiesch, J., Altfeld, M., Tolosa, E., Adams, E., Lange, U., Gacrica-Beltran W. (2025). HLA-F expression on CD4 T cells in HIV-1 is linked to the presence of viremia and modulated by KIR3DS1 Research Square; URI

Gorgulho J, Trenkner T, Kinkel E, Fritzsche B, Kachel P, Peine S, Matschl U, Altfeld M, Huber S, Lohse AW, Alsdorf W, Bokemeyer C, Hoelzemer A, Beltran WG, von Felden J (2025). A dual compartment peripheral blood signature of soluble and membrane-bound immune checkpoints predicts outcome in lymphoma patients. Oncoimmunology. 14/2025; PubMed

Naidoo KK, Highton AJ, Baiyegunhi OO, Bhengu SP, Dong KL, Bunders MJ, Altfeld M, Ndung'u T (2024). Early Initiation of Antiretroviral Therapy Preserves the Metabolic Function of CD4+ T Cells in Subtype C Human Immunodeficiency Virus 1 Infection. J Infect Dis. 229/2024; PubMed

Winschel I, Willing A, Engler JB, Walkenhorst M, Meurs N, Binkle-Ladisch L, Woo MS, Pfeffer LK, Sonner JK, Borgmeyer U, Hagen SH, Grünhagel B, Claussen JM, Altfeld M, Friese MA (2024). Sex- and species-specific contribution of CD99 to T cell costimulation during multiple sclerosis. Biol Sex Differ. 15/2024; PubMed

Padoan B, Casar C, Krause J, Schultheiss C, Baumdick ME, Niehrs A, Zecher BF, Pujantell M, Yuki Y, Martin M, Remmerswaal EBM, Dekker T, van der Bom-Baylon ND, Noble JA, Carrington M, Bemelman FJ, van Lier RAW, Binder M, Gagliani N, Bunders MJ, Altfeld M (2024). NKp44/HLA-DP-dependent regulation of CD8 effector T cells by NK cells. Cell Rep. 43/2024; PubMed

Joshi VR, Altfeld M (2024). Harnessing natural killer cells to target HIV-1 persistence. Curr Opin HIV AIDS. 19/2024; PubMed

Thiele RJ, Grünhagel B, Muenchhoff M, Pujantell-Graell M, Jocham L, Düsedau A, Hennesen J, Hildebrandt H, Hagen SH, Sandfort D, Bunders MJ, Keppler OT, Hoffmann C, Altfeld M (2024). Magnitude of Type I Interferon Responses by Plasmacytoid Dendritic Cells After TLR7 Stimulation Is Associated With Human Immunodeficiency Virus Type 1 (HIV-1) Reservoir Sizes in Cisgender Women With HIV-1 on Antiretroviral Therapy. J Infect Dis. 229/2024; PubMed

Altfeld M, Müller-Trutwin M (2024). Allogeneic Natural Killer Cells: An Additional Player in Human Immunodeficiency Virus Cure Approaches? J Infect Dis. 229/2024; PubMed

Zecher BF, Ellinghaus D, Schloer S, Niehrs A, Padoan B, Baumdick ME, Yuki Y, Martin MP, Glow D, Schröder-Schwarz J, Niersch J, Brias S, Müller LM, Habermann R, Kretschmer P, Früh T, Dänekas J, Wehmeyer MH, Poch T, Sebode M, , Ellinghaus E, Degenhardt F, Körner C, Hoelzemer A, Fehse B, Oldhafer KJ, Schumacher U, Sauter G, Carrington M, Franke A, Bunders MJ, Schramm C, Altfeld M (2024). HLA-DPA1*02:01~B1*01:01 is a risk haplotype for primary sclerosing cholangitis mediating activation of NKp44+ NK cells. Gut. 73/2024; PubMed

Naidoo KK, Altfeld M (2024). The Role of Natural Killer Cells and Their Metabolism in HIV-1 Infection. Viruses. 16/2024; PubMed

Gorgulho J, Loosen SH, Masood R, Giehren F, Pagani F, Buescher G, Kocheise L, Joerg V, Schmidt C, Schulze K, Roderburg C, Kinkel E, Fritzsche B, Wehmeyer S, Schmidt B, Kachel P, Rolling C, Götze J, Busch A, Sinn M, Pereira-Veiga T, Wikman H, Geffken M, Peine S, Matschl U, Altfeld M, Huber S, Lohse AW, Beier F, Brümmendorf TH, Bokemeyer C, Luedde T, von Felden J (2024). Soluble and EV-bound CD27 act as antagonistic biomarkers in patients with solid tumors undergoing immunotherapy. J Exp Clin Cancer Res. 43/2024; PubMed

Pujantell M, Skenteris NT, Claussen JM, Grünhagel B, Thiele RJ, Altfeld M (2023). Sex-dependent differences in type I IFN-induced natural killer cell activation. Front Immunol. 14/2023; PubMed

Grünhagel B, Borggrewe M, Hagen SH, Ziegler SM, Henseling F, Glau L, Thiele RJ, Pujantell M, Sivayoganathan V, Padoan B, Claussen JM, Düsedau A, Hennesen J, Bunders MJ, Bonn S, Tolosa E, Krebs CF, Dorn C, Altfeld M (2023). Reduction of IFN-I responses by plasmacytoid dendritic cells in a longitudinal trans men cohort. iScience. 26/2023; PubMed

Naidoo K, Altfeld M (2023). SARS-CoV-2 exploits innate miscommunication for persistence. Nat Immunol. 24/2023; PubMed

Akiso M, Ameka M, Naidoo K, Langat R, Kombo J, Sikuku D, Ndung'u T, Altfeld M, Anzala O, Mureithi M (2023). Metabolic and mitochondrial dysregulation in CD4+ T cells from HIV-positive women on combination anti-retroviral therapy. PLoS One. 18/2023; PubMed

Altfeld M, Scully EP (2023). Sex Differences in HIV Infection. Curr Top Microbiol Immunol. 441/2023; PubMed

Peiseler M, Araujo David B, Zindel J, Surewaard BGJ, Lee WY, Heymann F, Nusse Y, Castanheira FVS, Shim R, Guillot A, Bruneau A, Atif J, Perciani C, Ohland C, Ganguli Mukherjee P, Niehrs A, Thuenauer R, Altfeld M, Amrein M, Liu Z, Gordon PMK, McCoy K, Deniset J, MacParland S, Ginhoux F, Tacke F, Kubes P (2023). Kupffer cell-like syncytia replenish resident macrophage function in the fibrotic liver. Science. 381/2023; PubMed

Möller KJ, Wegner LHM, Malsy J, Baumdick ME, Borggrewe M, Jordan-Paiz A, Jung JM, Martrus G, Kretschmer P, Sagebiel AF, Schreurs RRCE, Hagen SH, Burmester G, Clauditz TS, Pals ST, Boettcher M, Melling N, Sauter G, Tomuschat C, Königs I, Schumacher U, Altfeld M, Bernink JH, Perez D, Reinshagen K, Bunders MJ (2023). Expanded ILC2s in human infant intestines promote tissue growth. Mucosal Immunol. 16/2023; PubMed

Zhang Z, Duri K, Duisters KLW, Schoeman JC, Chandiwana P, Lindenburg P, Jaeger J, Ziegler S, Altfeld M, Kohler I, Harms A, Gumbo FZ, Hankemeier T, Bunders MJ (2023). Altered methionine-sulfone levels are associated with impaired growth in HIV-exposed-uninfected children. AIDS. 37/2023; PubMed

Ufer F, Ziegler SM, Altfeld M, Friese MA (2023). Case report: JAK inhibition as promising treatment option of fatal RVCLS due to TREX1 mutation (pVAL235Glyfs*6). Front Neurol. 14/2023; PubMed

Ziegler AE, Fittje P, Müller LM, Ahrenstorf AE, Hagemann K, Hagen SH, Hess LU, Niehrs A, Poch T, Ravichandran G, Löbl SM, Padoan B, Brias S, Hennesen J, Richard M, Richert L, Peine S, Oldhafer KJ, Fischer L, Schramm C, Martrus G, Bunders MJ, Altfeld M, Lunemann S (2023). The co-inhibitory receptor TIGIT regulates NK cell function and is upregulated in human intrahepatic CD56bright NK cells. Front Immunol. 14/2023; PubMed

Beisel C, Jordan-Paiz A, Köllmann S, Ahrenstorf AE, Padoan B, Barkhausen T, Addo MM, Altfeld M (2023). Sex differences in the percentage of IRF5 positive B cells are associated with higher production of TNF-α in women in response to TLR9 in humans. Biol Sex Differ. 14/2023; PubMed

Jordan-Paiz A, Martrus G, Steinert FL, Kaufmann M, Sagebiel AF, Schreurs RRCE, Rechtien A, Baumdick ME, Jung JM, Möller KJ, Wegner L, Grüttner C, Richert L, Thünauer R, Schroeder-Schwarz J, van Goudoever JB, Geijtenbeek TBH, Altfeld M, Pals ST, Perez D, Klarenbeek PL, Tomuschat C, Sauter G, Königs I, Schumacher U, Friese MA, Melling N, Reinshagen K, Bunders MJ (2023). CXCR5+PD-1++ CD4+ T cells colonize infant intestines early in life and promote B cell maturation. Cell Mol Immunol. 20/2023; PubMed

Jost S, Lucar O, Lee E, Yoder T, Kroll K, Sugawara S, Smith S, Jones R, Tweet G, Werner A, Tomezsko PJ, Dugan HL, Ghofrani J, Rascle P, Altfeld M, Müller-Trutwin M, Goepfert P, Reeves RK (2023). Antigen-specific memory NK cell responses against HIV and influenza use the NKG2/HLA-E axis. Sci Immunol. 8/2023; PubMed

Baumdick ME, Niehrs A, Degenhardt F, Schwerk M, Hinrichs O, Jordan-Paiz A, Padoan B, Wegner LHM, Schloer S, Zecher BF, Malsy J, Joshi VR, Illig C, Schröder-Schwarz J, Möller KJ, , Martin MP, Yuki Y, Ozawa M, Sauter J, Schmidt AH, Perez D, Giannou AD, Carrington M, Davis RS, Schumacher U, Sauter G, Huber S, Puelles VG, Melling N, Franke A, , Altfeld M, Bunders MJ (2023). HLA-DP on Epithelial Cells Enables Tissue Damage by NKp44+ Natural Killer Cells in Ulcerative Colitis. Gastroenterology. 165/2023; PubMed

Lücke J, Heinrich F, Malsy J, Meins N, Schnell J, Böttcher M, Nawrocki M, Zhang T, Bertram F, Sabihi M, Kempski J, Blankenburg T, Duprée A, Reeh M, Wolter S, Mann O, Izbicki JR, Lohse AW, Gagliani N, Lütgehetmann M, Bunders MJ, Altfeld M, Sauter G, Giannou AD, Krasemann S, Ondruschka B, Huber S (2023). Intestinal IL-1β Plays a Role in Protecting against SARS-CoV-2 Infection. J Immunol. 211/2023; PubMed

Cords L, Woost R, Kummer S, Brehm TT, Kluge S, Schmiedel S, Jordan S, Lohse AW, Altfeld M, Addo MM, Schulze Zur Wiesch J, Beisel C (2022). Frequency of IRF5+ dendritic cells is associated with the TLR7-induced inflammatory cytokine response in SARS-CoV-2 infection. Cytokine. 162/2023; PubMed

Vollmers S, Lobermeyer A, Niehrs A, Fittje P, Indenbirken D, Nakel J, Virdi S, Brias S, Trenkner T, Sauer G, Peine S, Behrens GMN, Lehmann C, Meurer A, Pauli R, Postel N, Roider J, Scholten S, Spinner CD, Stephan C, Wolf E, Wyen C, Richert L, Norman PJ, Sauter J, Schmidt AH, Hoelzemer A, Altfeld M, Körner C (2022). Host KIR/HLA-C Genotypes Determine HIV-Mediated Changes of the NK Cell Repertoire and Are Associated With Vpu Sequence Variations Impacting Downmodulation of HLA-C. Front Immunol. 13/2022; PubMed

Müller AL, Casar C, Preti M, Krzikalla D, Gottwick C, Averhoff P, Rosenstiel P, Gelderblom M, Altfeld M, Lohse AW, Steinmann S, Sebode M, Krause J, Schwinge D, Schramm C, Carambia A, Herkel J (2022). Inflammatory type 2 conventional dendritic cells contribute to murine and human cholangitis. J Hepatol. 77/2022; PubMed

Höfle J, Trenkner T, Kleist N, Schwane V, Vollmers S, Barcelona B, Niehrs A, Fittje P, Huynh-Tran VH, Sauter J, Schmidt AH, Peine S, Hoelzemer A, Richert L, Altfeld M, Körner C (2022). Engagement of TRAIL triggers degranulation and IFNγ production in human natural killer cells. EMBO Rep. 23/2022; PubMed

Fittje P, Hœlzemer A, Garcia-Beltran WF, Vollmers S, Niehrs A, Hagemann K, Martrus G, Körner C, Kirchhoff F, Sauter D, Altfeld M (2022). HIV-1 Nef-mediated downregulation of CD155 results in viral restriction by KIR2DL5+ NK cells. PLoS Pathog. 18/2022; PubMed

Hagemann K, Riecken K, Jung JM, Hildebrandt H, Menzel S, Bunders MJ, Fehse B, Koch-Nolte F, Heinrich F, Peine S, Schulze Zur Wiesch J, Brehm TT, Addo MM, Lütgehetmann M, Altfeld M (2022). Natural killer cell-mediated ADCC in SARS-CoV-2-infected individuals and vaccine recipients. Eur J Immunol. 52/2022; PubMed

Sampson O, Lim N, White J, Vieira V, Kløverpris H, Adland E, Conlon C, Skelly D, Jones L, Stafford L, Jamsen A, Barnes E, Dunachie S, Frater J, Klenerman P, Altfeld M, Goulder P (2022). A simple, robust flow cytometry-based whole blood assay for investigating sex differential interferon alpha production by plasmacytoid dendritic cells. J Immunol Methods. 504/2022; PubMed

Klein K, Hölzemer A, Wang T, Kim TE, Dugan HL, Jost S, Altfeld M, Garcia-Beltran WF (2021). A Genome-Wide CRISPR/Cas9-Based Screen Identifies Heparan Sulfate Proteoglycans as Ligands of Killer-Cell Immunoglobulin-Like Receptors. Front Immunol. 12/2021; PubMed

Jung JM, Ching W, Baumdick ME, Hofmann-Sieber H, Bosse JB, Koyro T, Möller KJ, Wegner L, Niehrs A, Russu K, Ohms M, Zhang W, Ehrhardt A, Duisters K, Spierings E, Hölzemer A, Körner C, Jansen SA, Peine S, Königs I, Lütgehetmann M, Perez D, Reinshagen K, Lindemans CA, Altfeld M, Belderbos M, Dobner T, Bunders MJ (2021). KIR3DS1 directs NK cell-mediated protection against human adenovirus infections. Sci Immunol. 6/2021; PubMed

Hagen SH, Hennesen J, Altfeld M (2021). Assessment of escape from X chromosome inactivation and gene expression in single human immune cells. STAR Protoc. 2/2021; PubMed

Hambach J, Stähler T, Eden T, Wendt D, Tode N, Haag F, Tolosa E, Altfeld M, Fathi A, Dahlke C, Addo MM, Menzel S, Koch-Nolte F (2021). A simple, sensitive, and low-cost FACS assay for detecting antibodies against the native SARS-CoV-2 spike protein. Immun Inflamm Dis. 9/2021; PubMed

Poch T, Krause J, Casar C, Liwinski T, Glau L, Kaufmann M, Ahrenstorf AE, Hess LU, Ziegler AE, Martrus G, Lunemann S, Sebode M, Li J, Schwinge D, Krebs CF, Franke A, Friese MA, Oldhafer KJ, Fischer L, Altfeld M, Lohse AW, Huber S, Tolosa E, Gagliani N, Schramm C (2021). Single-cell atlas of hepatic T cells reveals expansion of liver-resident naive-like CD4+ T cells in primary sclerosing cholangitis. J Hepatol. 75/2021; PubMed

Ziegler MC, Naidoo K, Chapel A, Nkotwana S, Mann J, Mncube Z, Ismael N, Goulder P, Ndung'u T, Altfeld M, Thobakgale CF (2021). HIV-1 evades a Gag mutation that abrogates killer cell immunoglobulin-like receptor binding and disinhibits natural killer cells in infected individuals with KIR2DL2+/HLA-C*03: 04+ genotype. AIDS. 35/2021; PubMed

Garcia-Beltran WF, Claiborne DT, Maldini CR, Phelps M, Vrbanac V, Karpel ME, Krupp KL, Power KA, Boutwell CL, Balazs AB, Tager AM, Altfeld M, Allen TM (2021). Innate Immune Reconstitution in Humanized Bone Marrow-Liver-Thymus (HuBLT) Mice Governs Adaptive Cellular Immune Function and Responses to HIV-1 Infection. Front Immunol. 12/2021; PubMed

Mdletshe N, Thobakgale C, Malaba TR, Madlala H, Myer L, Muema DM, Mogeni P, Gray CM, Altfeld M, Newell ML, Ndung'u T (2021). Low Immune Activation in Early Pregnancy Is Associated With Preterm But Not Small-for-gestational-age Delivery in Women Infected With Human Immunodeficiency Virus Initiating Antiretroviral Therapy in Pregnancy: A Prematurity Immunology in HIV-infected Mothers and their Infants Study (PIMS) Case-control Study in Cape Town, South Africa. Clin Infect Dis. 73/2021; PubMed

Highton AJ, Schuster IS, Degli-Esposti MA, Altfeld M (2021). The role of natural killer cells in liver inflammation. Semin Immunopathol. 43/2021; PubMed

Koyro TF, Kraus E, Lunemann S, Hölzemer A, Wulf S, Jung J, Fittje P, Henseling F, Körner C, Huber TB, Grundhoff A, Wiech T, Panzer U, Fischer N, Altfeld M (2020). Upregulation of HLA-F expression by BK polyomavirus infection induces immune recognition by KIR3DS1-positive natural killer cells. Kidney Int. 99/2021; PubMed

Schwane V, Huynh-Tran VH, Vollmers S, Yakup VM, Sauter J, Schmidt AH, Peine S, Altfeld M, Richert L, Körner C (2020). Distinct Signatures in the Receptor Repertoire Discriminate CD56bright and CD56dim Natural Killer Cells. Front Immunol. 11/2020; PubMed

Offersen R, Yu WH, Scully EP, Julg B, Euler Z, Sadanand S, Garcia-Dominguez D, Zheng L, Rasmussen TA, Jennewein MF, Linde C, Sassic J, Lofano G, Vigano S, Stephenson KE, Fischinger S, Suscovich TJ, Lichterfeld M, Lauffenburger D, Rosenberg ES, Allen T, Altfeld M, Charles RC, Østergaard L, Tolstrup M, Barouch DH, Søgaard OS, Alter G (2020). HIV Antibody Fc N-Linked Glycosylation Is Associated with Viral Rebound. Cell Rep. 33/2020; PubMed

Hagen SH, Henseling F, Hennesen J, Savel H, Delahaye S, Richert L, Ziegler SM, Altfeld M (2020). Heterogeneous Escape from X Chromosome Inactivation Results in Sex Differences in Type I IFN Responses at the Single Human pDC Level. Cell Rep. 33/2020; PubMed

Highton AJ, Diercks BP, Möckl F, Martrus G, Sauter J, Schmidt AH, Bunders MJ, Körner C, Guse AH, Altfeld M (2020). High Metabolic Function and Resilience of NKG2A-Educated NK Cells. Front Immunol. 11/2020; PubMed

Bunders MJ, Altfeld M (2020). Implications of Sex Differences in Immunity for SARS-CoV-2 Pathogenesis and Design of Therapeutic Interventions. Immunity. 53/2020; PubMed

von Wenserski L, Schultheiß C, Bolz S, Schliffke S, Simnica D, Willscher E, Gerull H, Wolters-Eisfeld G, Riecken K, Fehse B, Altfeld M, Nollau P, Binder M (2020). SLAMF receptors negatively regulate B cell receptor signaling in chronic lymphocytic leukemia via recruitment of prohibitin-2. Leukemia. 35/2021; PubMed

Sellau J, Groneberg M, Fehling H, Thye T, Hoenow S, Marggraff C, Weskamm M, Hansen C, Stanelle-Bertram S, Kuehl S, Noll J, Wolf V, Metwally NG, Hagen SH, Dorn C, Wernecke J, Ittrich H, Tannich E, Jacobs T, Bruchhaus I, Altfeld M, Lotter H (2020). Androgens predispose males to monocyte-mediated immunopathology by inducing the expression of leukocyte recruitment factor CXCL1. Nat Commun. 11/2020; PubMed

Pflitsch C, Feldmann CN, Richert L, Hagen S, Diemert A, Goletzke J, Hecher K, Jazbutyte V, Renné T, Arck PC, Altfeld M, Ziegler S (2020). In-depth characterization of monocyte subsets during the course of healthy pregnancy. J Reprod Immunol. 141/2020; PubMed

Ziegler MC, Nelde A, Weber JK, Schreitmüller CM, Martrus G, Huynh T, Bunders MJ, Lunemann S, Stevanovic S, Zhou R, Altfeld M (2020). HIV-1 induced changes in HLA-C*03 :  04-presented peptide repertoires lead to reduced engagement of inhibitory natural killer cell receptors. AIDS. 34/2020; PubMed

Adland E, Millar J, Bengu N, Muenchhoff M, Fillis R, Sprenger K, Ntlantsana V, Roider J, Vieira V, Govender K, Adamson J, Nxele N, Ochsenbauer C, Kappes J, Mori L, van Lobenstein J, Graza Y, Chinniah K, Kapongo C, Bhoola R, Krishna M, Matthews PC, Poderos RP, Lluch MC, Puertas MC, Prado JG, McKerrow N, Archary M, Ndung'u T, Groll A, Jooste P, Martinez-Picado J, Altfeld M, Goulder P (2020). Author Correction: Sex-specific innate immune selection of HIV-1 in utero is associated with increased female susceptibility to infection. Nat Commun. 11/2020; PubMed

Adland E, Millar J, Bengu N, Muenchhoff M, Fillis R, Sprenger K, Ntlantsana V, Roider J, Vieira V, Govender K, Adamson J, Nxele N, Ochsenbauer C, Kappes J, Mori L, van Lobenstein J, Graza Y, Chinniah K, Kapongo C, Bhoola R, Krishna M, Matthews PC, Poderos RP, Lluch MC, Puertas MC, Prado JG, McKerrow N, Archary M, Ndung'u T, Groll A, Jooste P, Martinez-Picado J, Altfeld M, Goulder P (2020). Sex-specific innate immune selection of HIV-1 in utero is associated with increased female susceptibility to infection. Nat Commun. 11/2020; PubMed

Hess LU, Martrus G, Ziegler AE, Langeneckert AE, Salzberger W, Goebels H, Sagebiel AF, Hagen SH, Poch T, Ravichandran G, Koch M, Schramm C, Oldhafer KJ, Fischer L, Tiegs G, Richert L, Bunders MJ, Lunemann S, Altfeld M (2020). The Transcription Factor Promyelocytic Leukemia Zinc Finger Protein Is Associated With Expression of Liver-Homing Receptors on Human Blood CD56bright Natural Killer Cells. Hepatol Commun. 4/2020; PubMed

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Claiborne DT, Scully EP, Palmer CD, Prince JL, Macharia GN, Kopycinski J, Michelo CM, Wiener HW, Parker R, Nganou-Makamdop K, Douek D, Altfeld M, Gilmour J, Price MA, Tang J, Kilembe W, Allen SA, Hunter E (2019). Protective HLA alleles are associated with reduced LPS levels in acute HIV infection with implications for immune activation and pathogenesis. PLoS Pathog. 15/2019; PubMed

van Stigt Thans T, Akko JI, Niehrs A, Garcia-Beltran WF, Richert L, Stürzel CM, Ford CT, Li H, Ochsenbauer C, Kappes JC, Hahn BH, Kirchhoff F, Martrus G, Sauter D, Altfeld M, Hölzemer A (2019). Primary HIV-1 Strains Use Nef To Downmodulate HLA-E Surface Expression. J Virol. 93/2019; PubMed

Martrus G, Goebels H, Langeneckert AE, Kah J, Flomm F, Ziegler AE, Niehrs A, Löbl SM, Russu K, Hess LU, Salzberger W, Poch T, Nashan B, Schramm C, Oldhafer KJ, Dandri M, Koch M, Lunemann S, Altfeld M (2019). CD49a Expression Identifies a Subset of Intrahepatic Macrophages in Humans. Front Immunol. 10/2019; PubMed

Ravichandran G, Neumann K, Berkhout LK, Weidemann S, Langeneckert AE, Schwinge D, Poch T, Huber S, Schiller B, Hess LU, Ziegler AE, Oldhafer KJ, Barikbin R, Schramm C, Altfeld M, Tiegs G (2019). Interferon-γ-dependent immune responses contribute to the pathogenesis of sclerosing cholangitis in mice. J Hepatol. 71/2019; PubMed

Sagebiel AF, Steinert F, Lunemann S, Körner C, Schreurs RRCE, Altfeld M, Perez D, Reinshagen K, Bunders MJ (2019). Tissue-resident Eomes+ NK cells are the major innate lymphoid cell population in human infant intestine. Nat Commun. 10/2019; PubMed

Langeneckert AE, Lunemann S, Martrus G, Salzberger W, Hess LU, Ziegler AE, Poch T, Ravichandran G, Matschl U, Bosse JB, Tiegs G, Fischer L, Koch M, Herkel J, Oldhafer KJ, Schramm C, Altfeld M (2019). CCL21-expression and accumulation of CCR7+ NK cells in livers of patients with primary sclerosing cholangitis. Eur J Immunol. 49/2019; PubMed

Lunemann S, Langeneckert AE, Martrus G, Hess LU, Salzberger W, Ziegler AE, Löbl SM, Poch T, Ravichandran G, Sauter J, Schmidt AH, Schramm C, Oldhafer KJ, Altfeld M, Körner C (2019). Human liver-derived CXCR6+ NK cells are predominantly educated through NKG2A and show reduced cytokine production. J Leukoc Biol. 105/2019; PubMed

Scully EP, Gandhi M, Johnston R, Hoh R, Lockhart A, Dobrowolski C, Pagliuzza A, Milush JM, Baker CA, Girling V, Ellefson A, Gorelick R, Lifson J, Altfeld M, Alter G, Cedars M, Solomon A, Lewin SR, Karn J, Chomont N, Bacchetti P, Deeks SG (2019). Sex-Based Differences in Human Immunodeficiency Virus Type 1 Reservoir Activity and Residual Immune Activation. J Infect Dis. 219/2019; PubMed

Niehrs A, Garcia-Beltran WF, Norman PJ, Watson GM, Hölzemer A, Chapel A, Richert L, Pommerening-Röser A, Körner C, Ozawa M, Martrus G, Rossjohn J, Lee JH, Berry R, Carrington M, Altfeld M (2019). A subset of HLA-DP molecules serve as ligands for the natural cytotoxicity receptor NKp44. Nat Immunol. 20/2019; PubMed

Pfeifer C, Highton AJ, Peine S, Sauter J, Schmidt AH, Bunders MJ, Altfeld M, Körner C (2018). Natural Killer Cell Education Is Associated With a Distinct Glycolytic Profile. Front Immunol. 9/2018; PubMed

Ziegler MC, Grañana FB, Garcia-Beltran WF, Schulze Zur Wiesch J, Hoffmann C, Rechtien A, Lunemann S, Altfeld M (2018). Stable Frequencies of HLA-C*03:04/Peptide-Binding KIR2DL2/3+ Natural Killer Cells Following Vaccination. Front Immunol. 9/2018; PubMed

Lunemann S, Schöbel A, Kah J, Fittje P, Hölzemer A, Langeneckert AE, Hess LU, Poch T, Martrus G, Garcia-Beltran WF, Körner C, Ziegler AE, Richert L, Oldhafer KJ, Schulze Zur Wiesch J, Schramm C, Dandri M, Herker E, Altfeld M (2018). Interactions Between KIR3DS1 and HLA-F Activate Natural Killer Cells to Control HCV Replication in Cell Culture. Gastroenterology. 155/2018; PubMed

Salzberger W, Martrus G, Bachmann K, Goebels H, Heß L, Koch M, Langeneckert A, Lunemann S, Oldhafer KJ, Pfeifer C, Poch T, Richert L, Schramm C, Wahib R, Bunders MJ, Altfeld M (2018). Tissue-resident NK cells differ in their expression profile of the nutrient transporters Glut1, CD98 and CD71. PLoS One. 13/2018; PubMed

Ziegler SM, Feldmann CN, Hagen SH, Richert L, Barkhausen T, Goletzke J, Jazbutyte V, Martrus G, Salzberger W, Renné T, Hecher K, Diemert A, Arck PC, Altfeld M (2018). Innate immune responses to toll-like receptor stimulation are altered during the course of pregnancy. J Reprod Immunol. 128/2018; PubMed

Horst AK, Wegscheid C, Schaefers C, Schiller B, Neumann K, Lunemann S, Langeneckert AE, Oldhafer KJ, Weiler-Normann C, Lang KS, Singer BB, Altfeld M, Diehl L, Tiegs G (2018). Carcinoembryonic antigen-related cell adhesion molecule 1 controls IL-2-dependent regulatory T-cell induction in immune-mediated hepatitis in mice. Hepatology. 68/2018; PubMed

Biron CA, Altfeld M (2018). Is There Natural Killer Cell Memory and Can It Be Harnessed by Vaccination? Can Natural Killer and CD8 T Cells Switch Jobs? Cold Spring Harb Perspect Biol. 10/2018; PubMed

Bunders MJ, Altfeld M (2017). Can NK cells purge HIV sanctuaries? Nat Med. 23/2017; PubMed

Ziegler SM, Altfeld M (2017). Human Immunodeficiency Virus 1 and Type I Interferons-Where Sex Makes a Difference. Front Immunol. 8/2017; PubMed

Leitman EM, Palmer CD, Buus S, Chen F, Riddell L, Sims S, Klenerman P, Sáez-Cirión A, Walker BD, Hess PR, Altfeld M, Matthews PC, Goulder PJR (2017). Saporin-conjugated tetramers identify efficacious anti-HIV CD8+ T-cell specificities. PLoS One. 12/2017; PubMed

Rechtien A, Richert L, Lorenzo H, Martrus G, Hejblum B, Dahlke C, Kasonta R, Zinser M, Stubbe H, Matschl U, Lohse A, Krähling V, Eickmann M, Becker S, , Thiébaut R, Altfeld M, Addo MM (2017). Systems Vaccinology Identifies an Early Innate Immune Signature as a Correlate of Antibody Responses to the Ebola Vaccine rVSV-ZEBOV. Cell Rep. 20/2017; PubMed

Zulu MZ, Naidoo KK, Mncube Z, Jaggernath M, Goulder PJR, Ndung'u T, Altfeld M, Thobakgale CF (2017). Reduced Expression of Siglec-7, NKG2A, and CD57 on Terminally Differentiated CD56-CD16+ Natural Killer Cell Subset Is Associated with Natural Killer Cell Dysfunction in Chronic HIV-1 Clade C Infection. AIDS Res Hum Retroviruses. 33/2017; PubMed

Martrus G, Kautz T, Lunemann S, Richert L, Glau L, Salzberger W, Goebels H, Langeneckert A, Hess L, Poch T, Schramm C, Oldhafer KJ, Koch M, Tolosa E, Nashan B, Altfeld M (2017). Proliferative capacity exhibited by human liver-resident CD49a+CD25+ NK cells. PLoS One. 12/2017; PubMed

Lunemann S, Martrus G, Goebels H, Kautz T, Langeneckert A, Salzberger W, Koch M, J Bunders M, Nashan B, van Gisbergen KPJM, Altfeld M (2017). Hobit expression by a subset of human liver-resident CD56bright Natural Killer cells. Sci Rep. 7/2017; PubMed

Dulberger CL, McMurtrey CP, Hölzemer A, Neu KE, Liu V, Steinbach AM, Garcia-Beltran WF, Sulak M, Jabri B, Lynch VJ, Altfeld M, Hildebrand WH, Adams EJ (2017). Human Leukocyte Antigen F Presents Peptides and Regulates Immunity through Interactions with NK Cell Receptors. Immunity. 46/2017; PubMed

Chapel A, Garcia-Beltran WF, Hölzemer A, Ziegler M, Lunemann S, Martrus G, Altfeld M (2017). Peptide-specific engagement of the activating NK cell receptor KIR2DS1. Sci Rep. 7/2017; PubMed

Griesbeck M, Valantin MA, Lacombe K, Samri-Hassimi A, Bottero J, Blanc C, Sbihi Z, Zoorob R, Katlama C, Guiguet M, Altfeld M, Autran B, (2017). Hepatitis C virus drives increased type I interferon-associated impairments associated with fibrosis severity in antiretroviral treatment-treated HIV-1-hepatitis C virus-coinfected individuals. AIDS. 31/2017; PubMed

Beisel C, Ziegler S, Martrus Zapater G, Chapel A, Griesbeck M, Hildebrandt H, Lohse AW, Altfeld M (2017). TLR7-mediated activation of XBP1 correlates with the IFNα production in humans. Cytokine. 94/2017; PubMed

Angin M, Fathi A, King M, Ledoux MB, Piechocka-Trocha A, Altfeld M, Addo MM (2017). Acute HIV-1 infection is associated with increased plasma levels of heme oxygenase-1 and presence of heme oxygenase-1-specific regulatory T cells. AIDS. 31/2017; PubMed

Dierks P, Wroblewski R, Eberhard JM, Martrus G, Degen O, Hertling S, Schmiedel S, Lunemann S, Hüfner A, Lohse AW, Altfeld M, van Lunzen J, Schulze Zur Wiesch J (2017). Brief Report: Increased Frequency of CD39+ CD56bright Natural Killer Cells in HIV-1 Infection Correlates With Immune Activation and Disease Progression. J Acquir Immune Defic Syndr. 74/2017; PubMed

Ziegler SM, Beisel C, Sutter K, Griesbeck M, Hildebrandt H, Hagen SH, Dittmer U, Altfeld M (2017). Human pDCs display sex-specific differences in type I interferon subtypes and interferon α/β receptor expression. Eur J Immunol. 47/2017; PubMed

Dahlke C, Lunemann S, Kasonta R, Kreuels B, Schmiedel S, Ly ML, Fehling SK, Strecker T, Becker S, Altfeld M, Sow A, Lohse AW, Muñoz-Fontela C, Addo MM (2017). Comprehensive Characterization of Cellular Immune Responses Following Ebola Virus Infection. J Infect Dis. 215/2017; PubMed

Thobakgale C, Naidoo K, McKinnon LR, Werner L, Samsunder N, Karim SA, Ndungʼu T, Altfeld M, Naidoo K (2017). Interleukin 1-Beta (IL-1β) Production by Innate Cells Following TLR Stimulation Correlates With TB Recurrence in ART-Treated HIV-Infected Patients. J Acquir Immune Defic Syndr. 74/2017; PubMed

Körner C, Simoneau CR, Schommers P, Granoff M, Ziegler M, Hölzemer A, Lunemann S, Chukwukelu J, Corleis B, Naranbhai V, Kwon DS, Scully EP, Jost S, Kirchhoff F, Carrington M, Altfeld M (2017). HIV-1-Mediated Downmodulation of HLA-C Impacts Target Cell Recognition and Antiviral Activity of NK Cells. Cell Host Microbe. 22/2017; PubMed

Altfeld M, Bunders MJ (2016). Erratum to: Impact of HIV-1 infection on the feto-maternal crosstalk and consequences for pregnancy outcome and infant health. Semin Immunopathol. 38/2016; PubMed

Hagen S, Altfeld M (2016). The X awakens: multifactorial ramifications of sex-specific differences in HIV-1 infection. J Virus Erad. 2/2016; PubMed

Altfeld M, Bunders MJ (2016). Impact of HIV-1 infection on the feto-maternal crosstalk and consequences for pregnancy outcome and infant health. Semin Immunopathol. 38/2016; PubMed

Griesbeck M, Scully E, Altfeld M (2016). Sex and gender differences in HIV-1 infection. Clin Sci (Lond). 130/2016; PubMed

Tully DC, Ogilvie CB, Batorsky RE, Bean DJ, Power KA, Ghebremichael M, Bedard HE, Gladden AD, Seese AM, Amero MA, Lane K, McGrath G, Bazner SB, Tinsley J, Lennon NJ, Henn MR, Brumme ZL, Norris PJ, Rosenberg ES, Mayer KH, Jessen H, Kosakovsky Pond SL, Walker BD, Altfeld M, Carlson JM, Allen TM (2016). Differences in the Selection Bottleneck between Modes of Sexual Transmission Influence the Genetic Composition of the HIV-1 Founder Virus. PLoS Pathog. 12/2016; PubMed

Scully EP, Lockhart A, Garcia-Beltran W, Palmer CD, Musante C, Rosenberg E, Allen TM, Chang JJ, Bosch RJ, Altfeld M (2016). Innate immune reconstitution with suppression of HIV-1. JCI Insight. 1/2016; PubMed

He X, Simoneau CR, Granoff ME, Lunemann S, Dugast AS, Shao Y, Altfeld M, Körner C (2016). Assessment of the antiviral capacity of primary natural killer cells by optimized in vitro quantification of HIV-1 replication. J Immunol Methods. 434/2016; PubMed

Martrus G, Altfeld M (2016). Immunological strategies to target HIV persistence. Curr Opin HIV AIDS. 11/2016; PubMed

Gunn B, Schneider J, Shansab M, Bastian AR, Fahrbach K, Smith A, Mahan A, Karim M, Licht A, Zvonar I, Tedesco J, Anderson M, Chapel A, Suscovich T, Malaspina D, Streeck H, Walker BD, Kim A, Lauer G, Altfeld M, Pillai S, Szleifer I, Kelleher NL, Kiser PF, Hope TJ, Alter G (2016). Enhanced binding of antibodies generated during chronic HIV infection to mucus component MUC16. Mucosal Immunol. 9/2016; PubMed

Ziegler S, Altfeld M (2016). Sex differences in HIV-1-mediated immunopathology. Curr Opin HIV AIDS. 11/2016; PubMed

Sereti I, Altfeld M (2016). Immune activation and HIV: an enduring relationship. Curr Opin HIV AIDS. 11/2016; PubMed

Sips M, Liu Q, Draghi M, Ghebremichael M, Berger CT, Suscovich TJ, Sun Y, Walker BD, Carrington M, Altfeld M, Brouckaert P, De Jager PL, Alter G (2016). HLA-C levels impact natural killer cell subset distribution and function. Hum Immunol. 77/2016; PubMed

Garcia-Beltran WF, Hölzemer A, Martrus G, Chung AW, Pacheco Y, Simoneau CR, Rucevic M, Lamothe-Molina PA, Pertel T, Kim TE, Dugan H, Alter G, Dechanet-Merville J, Jost S, Carrington M, Altfeld M (2016). Open conformers of HLA-F are high-affinity ligands of the activating NK-cell receptor KIR3DS1. Nat Immunol. 17/2016; PubMed

Lunemann S, Martrus G, Hölzemer A, Chapel A, Ziegler M, Körner C, Garcia Beltran W, Carrington M, Wedemeyer H, Altfeld M (2016). Sequence variations in HCV core-derived epitopes alter binding of KIR2DL3 to HLA-C∗03:04 and modulate NK cell function. J Hepatol. 65/2016; PubMed

Martrus G, Niehrs A, Cornelis R, Rechtien A, García-Beltran W, Lütgehetmann M, Hoffmann C, Altfeld M (2016). Kinetics of HIV-1 Latency Reversal Quantified on the Single-Cell Level Using a Novel Flow-Based Technique. J Virol. 90/2016; PubMed

Schommers P, Martrus G, Matschl U, Sirignano M, Lütgehetmann M, Richert L, Hope TJ, Fätkenheuer G, Altfeld M (2016). Changes in HIV-1 Capsid Stability Induced by Common Cytotoxic-T-Lymphocyte-Driven Viral Sequence Mutations. J Virol. 90/2016; PubMed

Naranbhai V, de Assis Rosa D, Werner L, Moodley R, Hong H, Kharsany A, Mlisana K, Sibeko S, Garrett N, Chopera D, Carr WH, Abdool Karim Q, Hill AV, Abdool Karim SS, Altfeld M, Gray CM, Ndung'u T (2016). Killer-cell Immunoglobulin-like Receptor (KIR) gene profiles modify HIV disease course, not HIV acquisition in South African women. BMC Infect Dis. 16/2016; PubMed

Archary D, Seaton KE, Passmore JS, Werner L, Deal A, Dunphy LJ, Arnold KB, Yates NL, Lauffenburger DA, Bergin P, Liebenberg LJ, Samsunder N, Mureithi MW, Altfeld M, Garrett N, Karim QA, Karim SA, Morris L, Tomaras GD (2016). Distinct genital tract HIV-specific antibody profiles associated with tenofovir gel. Mucosal Immunol. 9/2016; PubMed

Salzberger W, Garcia-Beltran WF, Dugan H, Gubbala S, Simoneau C, Gressens SB, Jost S, Altfeld M (2015). Influence of Glycosylation Inhibition on the Binding of KIR3DL1 to HLA-B*57:01. PLoS One. 10/2015; PubMed

Palmer CD, Romero-Tejeda M, Sirignano M, Sharma S, Allen TM, Altfeld M, Jost S (2015). Naturally Occurring Subclinical Endotoxemia in Humans Alters Adaptive and Innate Immune Functions through Reduced MAPK and Increased STAT1 Phosphorylation. J Immunol. 196/2016; PubMed

Heesters BA, Lindqvist M, Vagefi PA, Scully EP, Schildberg FA, Altfeld M, Walker BD, Kaufmann DE, Carroll MC (2015). Follicular Dendritic Cells Retain Infectious HIV in Cycling Endosomes. PLoS Pathog. 11/2015; PubMed

Griesbeck M, Ziegler S, Laffont S, Smith N, Chauveau L, Tomezsko P, Sharei A, Kourjian G, Porichis F, Hart M, Palmer CD, Sirignano M, Beisel C, Hildebrandt H, Cénac C, Villani AC, Diefenbach TJ, Le Gall S, Schwartz O, Herbeuval JP, Autran B, Guéry JC, Chang JJ, Altfeld M (2015). Sex Differences in Plasmacytoid Dendritic Cell Levels of IRF5 Drive Higher IFN-α Production in Women. J Immunol. 195/2015; PubMed

Scully E, Lockhart A, Huang L, Robles Y, Becerril C, Romero-Tejeda M, Albrecht MA, Palmer CD, Bosch RJ, Altfeld M, Kuritzkes DR, Lin NH (2015). Elevated Levels of Microbial Translocation Markers and CCL2 Among Older HIV-1-Infected Men. J Infect Dis. 213/2016; PubMed

Agnandji ST, Huttner A, Zinser ME, Njuguna P, Dahlke C, Fernandes JF, Yerly S, Dayer JA, Kraehling V, Kasonta R, Adegnika AA, Altfeld M, Auderset F, Bache EB, Biedenkopf N, Borregaard S, Brosnahan JS, Burrow R, Combescure C, Desmeules J, Eickmann M, Fehling SK, Finckh A, Goncalves AR, Grobusch MP, Hooper J, Jambrecina A, Kabwende AL, Kaya G, Kimani D, Lell B, Lemaître B, Lohse AW, Massinga-Loembe M, Matthey A, Mordmüller B, Nolting A, Ogwang C, Ramharter M, Schmidt-Chanasit J, Schmiedel S, Silvera P, Stahl FR, Staines HM, Strecker T, Stubbe HC, Tsofa B, Zaki S, Fast P, Moorthy V, Kaiser L, Krishna S, Becker S, Kieny MP, Bejon P, Kremsner PG, Addo MM, Siegrist CA (2015). Phase 1 Trials of rVSV Ebola Vaccine in Africa and Europe. N Engl J Med. 374/2016; PubMed

Claiborne DT, Prince JL, Scully E, Macharia G, Micci L, Lawson B, Kopycinski J, Deymier MJ, Vanderford TH, Nganou-Makamdop K, Ende Z, Brooks K, Tang J, Yu T, Lakhi S, Kilembe W, Silvestri G, Douek D, Goepfert PA, Price MA, Allen SA, Paiardini M, Altfeld M, Gilmour J, Hunter E (2015). Replicative fitness of transmitted HIV-1 drives acute immune activation, proviral load in memory CD4+ T cells, and disease progression. Proc Natl Acad Sci U S A. 112/2015; PubMed

Hölzemer A, Thobakgale CF, Jimenez Cruz CA, Garcia-Beltran WF, Carlson JM, van Teijlingen NH, Mann JK, Jaggernath M, Kang SG, Körner C, Chung AW, Schafer JL, Evans DT, Alter G, Walker BD, Goulder PJ, Carrington M, Hartmann P, Pertel T, Zhou R, Ndung'u T, Altfeld M (2015). Selection of an HLA-C*03:04-Restricted HIV-1 p24 Gag Sequence Variant Is Associated with Viral Escape from KIR2DL3+ Natural Killer Cells: Data from an Observational Cohort in South Africa. PLoS Med. 12/2015; PubMed

Reeves RK, Li H, Jost S, Blass E, Li H, Schafer JL, Varner V, Manickam C, Eslamizar L, Altfeld M, von Andrian UH, Barouch DH (2015). Antigen-specific NK cell memory in rhesus macaques. Nat Immunol. 16/2015; PubMed

Rokx C, Richman DD, Müller-Trutwin M, Silvestri G, Lunzen J, Khoo S, Lichterfeld M, Altfeld M, Perno CF, Hunt PW, Mallon P, Rockstroh JK, Pozniak AL, Clotet B, Boucher CA (2015). Second European Round Table on the Future Management of HIV: 10-11 October 2014, Barcelona, Spain. J Virus Erad. 1/2015; PubMed

Altfeld M, Gale M (2015). Innate immunity against HIV-1 infection. Nat Immunol. 16/2015; PubMed

Cohen K, Altfeld M, Alter G, Stamatatos L (2014). Early preservation of CXCR5+ PD-1+ helper T cells and B cell activation predict the breadth of neutralizing antibody responses in chronic HIV-1 infection. J Virol. 88/2014; PubMed

Addo MM, Altfeld M (2014). Sex-based differences in HIV type 1 pathogenesis. J Infect Dis. 209 Suppl 3/2014; PubMed

van Lunzen J, Altfeld M (2014). Sex differences in infectious diseases-common but neglected. J Infect Dis. 209 Suppl 3/2014; PubMed

Jost S, Tomezsko PJ, Rands K, Toth I, Lichterfeld M, Gandhi RT, Altfeld M (2014). CD4+ T-cell help enhances NK cell function following therapeutic HIV-1 vaccination. J Virol. 88/2014; PubMed

Vaidya SA, Korner C, Sirignano MN, Amero M, Bazner S, Rychert J, Allen TM, Rosenberg ES, Bosch RJ, Altfeld M (2014). Tumor necrosis factor α is associated with viral control and early disease progression in patients with HIV type 1 infection. J Infect Dis. 210/2014; PubMed

Streeck H, Lu R, Beckwith N, Milazzo M, Liu M, Routy JP, Little S, Jessen H, Kelleher AD, Hecht F, Sekaly RP, Alter G, Heckerman D, Carrington M, Rosenberg ES, Altfeld M (2014). Emergence of individual HIV-specific CD8 T cell responses during primary HIV-1 infection can determine long-term disease outcome. J Virol. 88/2014; PubMed

van Teijlingen NH, Hölzemer A, Körner C, García-Beltrán WF, Schafer JL, Fadda L, Suscovich TJ, Brander C, Carrington M, Evans DT, van Baarle D, Altfeld M (2014). Sequence variations in HIV-1 p24 Gag-derived epitopes can alter binding of KIR2DL2 to HLA-C*03:04 and modulate primary natural killer cell function. AIDS. 28/2014; PubMed

Simmons RP, Scully EP, Groden EE, Arnold KB, Chang JJ, Lane K, Lifson J, Rosenberg E, Lauffenburger DA, Altfeld M (2013). HIV-1 infection induces strong production of IP-10 through TLR7/9-dependent pathways. AIDS. 27/2013; PubMed